Immunocompetent ex vivo human skin platforms

Human data generation ahead of clinical trials

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DISCOVER OUR UNIQUE SPATIAL BIOLOGY PLATFORM

Study skin cell interaction & response

INCLUDE SPATIAL CONTEXT IN YOUR DATA

Genoskin launches MANTIS®, a unique spatial skin biology platform to study human skin cells within their spatial context. Combined with our functional and immunocompetent human skin models, this innovative tool helps you obtain relevant and reliable data on the response of real human skin to your vaccine, drug or cosmetic and provides crucial information on cell interaction and on the simultaneous response of different cells to the compound you’re studying.

INNOVATIVE EX VIVO HUMAN SKIN MODELS USING HI-TECH SCIENCE

Living & functional human skin for human data generation

Genoskin is a Partner Research Organization (PRO) with unique expertise in skin & immunology. We aim to disrupt drug development by changing the way human data is generated to enable better, faster, safer drug development. Our proprietary ex vivo human skin platforms represent last-line screens, under laboratory conditions, prior to clinical evaluation. Our technologies only include natural human skin obtained from screenable patients cohort. The skin is maintained in a living and functional state for several days in order to help you obtain relevant data.

EX VIVO HUMAN SKIN MODELS.

IMAGINE THE POSSIBILITIES…

Going through an extensive, comprehensive research & development process is a challenge. You need to be quick and accurate to identify the optimal formulation,
The speed at which you can generate reliable human data becomes critical: the best way to generate that data is to use living human tissue.
Genoskin’s innovative technology and services enable precisely that.

Ethical & reliable skin models.

Genoskin’s human skin models provide a reliable alternative to animal experiments. Our models use donated human skin that is obtained with the donors’  informed consent in accordance with all applicable regulations.

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Real human skin structure
Live human skin response
Adequate skin barrier function, tissue integrity, morphology and physiology
All the characteristics and appendages of real human skin
Ready to use and easy to manipulate for efficient assays
Standardized for reproducible results
Variation of skin types and donors
Safety tested

Genoskin Human Skin Models

Our wide range of human skin models offers new testing possibilities to industries to test the response of human skin to their products.

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Ready-to-use human skin models

Operators can start testing immediately after following the instructions for use.

Preserved tissue integrity and cell viability

After 7 days of culture, Nativeskin® still demonstrates normal histological features.

ETHICAL EX VIVO HUMAN SKIN MODELS FROM REAL HUMAN SKIN TISSUE

Genoskin uses real human skin that is collected from volunteering donors

To provide the best skin models possible, Genoskin uses real human skin that is collected from volunteering donors. All our donors expressly consent to donating excess tissue after surgery to help science move forward while preserving animal welfare. Our human skin models therefore hold all the characteristics and appendages of real human skin and allow you to test your products on an innovative skin model that provides adequate skin barrier function, tissue integrity, morphology and physiology. Every skin sample is tested for safety before it is integrated in our testing kits.

Authorization AC-2011-1443 from the French Ministry of Research and Higher Education
Informed Consent from every donor
Skin samples and biopsies are collected in compliance to all applicable regulations
Approved by the Ethical Committees
Secure agreements with the contributing Hospitals and Clinics
In compliance with all applicable regulations.

Human skin models as an alternative to animal testing

Genoskin’s human skin models provide an excellent alternative to animal testing, as they contain no animal components. We strongly believe it’s possible to help science move forward by thinking out of the box to preserve animal welfare.

The closest alternative to in vivo clinical testing without using animals
Better predictiveness thanks to the use of living human skin
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