Overview of scientific publications

Examples of how our Models & Services can be used

Publications in scientific journals & magazines

Most Recent Scientific Publications

Genoskin aims to change drug development as we know it by using cutting-edge technology to make science move forward. Below you’ll find a list of publications that validate and/or use our unique technology and skin models for a wide range of applications. Simply click on the + sign to obtain more details and to access the publication of your choice.

November 2024 - Advancing understanding of human variability through toxicokinetic modeling, in vitro-in vivo extrapolation, and new approach methodologies.

October 2024 - Full-Thickness Perfused Skin-on-a-Chip with In Vivo-Like Drug Response for Drug and Cosmetics Testing.

Full-Thickness Perfused Skin-on-a-Chip with In Vivo-Like Drug Response for Drug and Cosmetics Testing.
Published in Bioengineering – October, 2024. https://doi.org/10.3390/bioengineering11111055.
Stephen Rhee, Chunguang Xia, Aditya Chandra, Morgan Hamon, Geonhui Lee, Chen Yang, Zaixun Guo, Bingjie Sun

Septembre 2024 - Peptide Drones Facilitating the Transdermal Delivery of Antitumor Proteins for Melanoma Treatment.

Peptide Drones Facilitating the Transdermal Delivery of Antitumor Proteins for Melanoma Treatment.
Published in Advance Functional materials – September, 2024. https://doi.org/10.1002/adfm.202412160.
Hyunji Kim, Suin Kim, Guewha Lee, Ji-eun Kim, Woo-jin Jeong

Septembre 2024 - Rheological and lipid caracterization of Minipig and human Skin Tissue: A comparative Study Across Different Locations and Depths.

August 2024 - Multimodal profiling of biostabilized human skin modules reveals a coordinated ecosystem response to injected mRNA-1273 COVID-19 vaccine.

Multimodal profiling of biostabilized human skin modules reveals a coordinated ecosystem response to injected mRNA-1273 COVID-19 vaccine.
Published in Allergy – August, 2024. https://doi.org/10.1111/all.16273.
Manon Scholaert, Mathias Peries, Emilie Braun, Jeremy Martin, Nadine Serhan, Alexia Loste, Audrey Bruner, Lilian Basso, Benoît Chaput, Eric Merle, Pascal Descargues, Emeline Pagès, Nicolas Gaudenzio.

August 2024 - 3D-printed tool for creating standardized burn wounds in ex vivo skin tissues.

3D-printed tool for creating standardized burn wounds in ex vivo skin tissues.
Published in ScienceDirect – August, 2024. https://doi.org/10.1016/j.stlm.2024.100162.
Mojtaba Javid, Fahimeh Tabatabaei.

June 2024 - Investigating Snake-Venom-Induced Dermonecrosis and Inflammation Using an Ex Vivo Human Skin Model.

Investigating Snake-Venom-Induced Dermonecrosis and Inflammation Using an Ex Vivo Human Skin Model.
Published by Toxins – June 17, 2024. Toxins 2024, 16(6), 276; https://doi.org/10.3390/toxins16060276.
Jaffer Alsolaiss, Gail Leeming, Rachael Da Silva, Nessrin Alomran, Nicholas R. Casewell, Abdulrazaq G. Habib, Robert A. Harrison and Cassandra M. Modahl.

June 2024 - The Prolyl Endopeptidase PREP Is Involved in Filaggrinolysis and Cornification.

The Prolyl Endopeptidase PREP Is Involved in Filaggrinolysis and Cornification.
Published in Journal of Investigative Dermatology – June 13, 2024. https://doi.org/10.1016/j.jid.2024.04.028.
Julie Briot, Carole Pon, Aude Foucher, Dominique Goudounèche, Nicolas Gaudenzio, Mark Donovan, Dominique Bernard, Marie-Claire Méchin, Michel Simon.

June 2024 - Challenges in Psoriasis Research: A Systematic Review of Preclinical Models.

Challenges in Psoriasis Research: A Systematic Review of Preclinical Models.
Published in Karger – June 10, 2024. https://doi.org/10.1159/000538993.
Ana Ubago-Rodríguez, María I. Quiñones-Vico, Manuel Sánchez-Díaz, Raquel Sanabria-de la Torre, Álvaro Sierra-Sánchez, Trinidad Montero-Vílchez, Ana Fernández-González, Salvador Arias-Santiago.

June 2024 - Towards the Development of a Cream with Antiviral Properties Targeting Both the Influenza A Virus and SARS-CoV-2.

Towards the Development of a Cream with Antiviral Properties Targeting Both the Influenza A Virus and SARS-CoV-2.
Published in Cosmetics – June 04, 2024. https://doi.org/10.3390/cosmetics11030091.
Philippe Mangeot, Kristell Lazou, Aurelia Blin, Valerie Gorzelanczyk, Olivier Jeanneton, Chantal Kurfurst, Karl Pays, Bruno Bavouzet, Carine Nizard, Theophile Ohlmann, Anne-Laure Bulteau.

May 2024 - Transdermal Sensing of Enzyme Biomarker Enabled by Chemo-Responsive Probe-Modified Epidermal Microneedle Patch in Human Skin Tissue.

Transdermal Sensing of Enzyme Biomarker Enabled by Chemo-Responsive Probe-Modified Epidermal Microneedle Patch in Human Skin Tissue.
Published in Advanced Materials Wiley – May 11, 2024. https://doi.org/10.1002/adma.202403758.
Nazanin Poursharifi, Morteza Hassanpouramiri, Alexander Zink, Muhammed Ucuncu, Onur Parlak.

May 2024 - Exploring allergic and irritant contact dermatitis - Biomarkers, mechanisms and allergen uptake.

Exploring allergic and irritant contact dermatitis – Biomarkers, mechanisms and allergen uptake.
Published by Karolinska Institutet – May 31, 2024. ISBN 978-91-8017-331-5.
Paulina Werner Nosrati

March 2024 - In vitro studies into establishing therapeutic bioequivalence of complex topical products: weight of evidence.

In vitro studies into establishing therapeutic bioequivalence of complex topical products: weight of evidence.
Published in Science Direct – March 25, 2024. 124012. https://doi.org/10.1016/j.ijpharm.2024.124012.
Margarida Miranda, Zoe Volmer, Alicia Cornick, Aidan Goody, Catarina Cardoso, Alberto A.C.C. Pais, Marc Brown, Carla Vitorino

December 2023 - Discovery of a structural class of antibiotics with explainable deep learning.

Discovery of a structural class of antibiotics with explainable deep learning.
Published in Nature – December 20, 2023. 626, pages177–185 (2024).
Felix Wong, Erica J. Zheng, Jacqueline A. Valeri, Nina M. Donghia, Melis N. Anahtar, Satotaka Omori, Alicia Li, Andres Cubillos-Ruiz, Aarti Krishnan, Wengong Jin, Abigail L. Manson, Jens Friedrichs, Ralf Helbig, Behnoush Hajian, Dawid K. Fiejtek, Florence F. Wagner, Holly H. Soutter, Ashlee M. Earl, Jonathan M. Stokes, Lars D. Renner & James J. Collins

December 2023 - MeXpose - A modular imaging pipeline for the quantitative assessment of cellular metal bioaccumulation.

MeXpose – A modular imaging pipeline for the quantitative assessment of cellular metal bioaccumulation.
Published in bioRxiv – December 15, 2023. https://doi.org/10.1101/2023.12.15.571675.
Gabriel Braun, Martin Schaier, Paulina Werner, Sarah Theiner, Jürgen Zanghellini, Lukas Wisgrill, Nanna Fyhrquist, Gunda Koellensperger

December 2023 - Redefine photoprotection: Sun protection beyond sunburn.

Redefine photoprotection: Sun protection beyond sunburn.
Published in Experimental dermatology Wiley – December 15, 2023. Exp Dermatol. 2024;33:e15002. doi:10.1111/exd.15002.
Mirja van Bodegraven, Marius Kröger, Daniela F. Zamudio Díaz, Silke B. Lohan, Rose K. C. Moritz, Nadine Möller, Chiara Knoblich, Alexandra Vogelsang, Zorica Milinic, Matthias Hallhuber, Julia M. Weise, Ludger Kolbe, Julia Gallinger, Cindy Graupner, Holger Klose, Claas Ulrich, Martina C. Meinke

December 2023 - The Development of Human Ex Vivo Models of Inflammatory Skin Conditions.

The Development of Human Ex Vivo Models of Inflammatory Skin Conditions.
Published in National Library of Medicine – December 8, 2023. Int J Mol Sci. 2023 Dec;24(24):17255. doi:10.3390/ijms242417255.
Eddy Hsi Chun Wang, Rebecca Barresi-Thornton, Li-Chi Chen, Maryanne Makredes Senna, I-Chien Liao, Ying Chen, Qian Zheng, Charbel Bouez

November 2023 - N-acetyl-L-hydroxyproline: A potent skin anti-ageing active preventing advanced glycation end-product formation in vitro and ex vivo

N-acetyl-L-hydroxyproline: A potent skin anti-ageing active preventing advanced glycation end-product formation in vitro and ex vivo
Published in International of Cosmetics Science – November 27, 2023.
Chiara Knoblich, Katja Dunckelmann, Andrea Krüger, Thomas Küper, Thomas Blatt, Julia M Weise

September 2023 - Household laundry detergents disrupt barrier integrity and induce inflammation in mouse and human skin

Household laundry detergents disrupt barrier integrity and induce inflammation in mouse and human skin
Published in European Journal of Allergy and Clinical Immunology, 2023 – September 27, 2023.
Arturo O. Rinaldi, Manru Li, Elena Barletta, Paolo D’Avino, Duygu Yazici, Yagiz Pat, Siobhan Ward, Daniel Burla, Ge Tan, Nima Askary, Rasmus Larsson, Jeremy Bost, Huseyn Babayev, Raja Dhir, Nicolas Gaudenzio, Mubeccel Akdis, Kari Nadeau, Cezmi A. Akdis, Yasutaka Mitamura

August 2023 - Copper-based dressing: Efficacy in a wound infection of ex vivo human skin

Copper-based dressing: Efficacy in a wound infection of ex vivo human skin
Published in Tissue&Cell (Volume 84, October 2023, 102196) – August 22, 2023.
Aaron D. Strickland, Mehmet Ozturk, Tricia Conti, Fahimeh Tabatabaei

August 2023 - M1/M2 Macrophage Skewing is Related to Reduction in Type I, V and VI Collagens with Aging in Sun-exposed Human Skin

M1/M2 Macrophage Skewing is Related to Reduction in Type I, V and VI Collagens with Aging in Sun-exposed Human Skin
Published in JID Innovations, 2023, 100222, ISSN 2667-0267 – August 11, 2023.
Satoshi Horiba, Munetaka Kawamoto, Ryozo Tobita, Ryota Kami, Yuki Ogura, Junichi Hosoi

August 2023 - Evaluating the Impact of Hair Care Product Exposure on Hair Follicle and Scalp Health

Evaluating the Impact of Hair Care Product Exposure on Hair Follicle and Scalp Health.
Published in Alternatives to Laboratory Animals (ATLA) – 2023;0(0).
Fung ES, Parker JA, Monnot AD.

August 2023 - Hydrogel degradation promotes angiogenic and regenerative potential of cell spheroids for wound healing

Hydrogel degradation promotes angiogenic and regenerative potential of cell spheroids for wound healing.
Published in Materials Today Bio – Volume 22, 2023,100769, ISSN 2590-0064; Published: 29 September 2022.
Victoria L. Thai, David H. Ramos-Rodriguez, Meron Mesfin, J. Kent Leach.

July 2023 - Engineering a versatile and retrievable cell macroencapsulation device for the delivery of therapeutic proteins.

Engineering a versatile and retrievable cell macroencapsulation device for the delivery of therapeutic proteins.
Published in iScience, Volume 26, Issue 8, 2023, 107372, ISSN 2589-0042 – July 12, 2023.
Julien Grogg, Remi Vernet, Emily Charrier, Muriel Urwyler, Olivier Von Rohr, Valentin Saingier, Fabien Courtout, Aurelien Lathuiliere, Nicolas Gaudenzio, Adrien Engel, Nicolas Mach.

June 2023 - 3D deconvolution of human skin immune architecture with Multiplex Annotated Tissue Imaging System.

3D deconvolution of human skin immune architecture with Multiplex Annotated Tissue Imaging System.
Published in ScienceAdvances, doi: 10.1126/sciadv.adf9491 – June 07, 2023.
Scholaert M., Houmadi R., Martin J., Serhan N., Tauber M., Braun E., Basso L., Merle E., Descargues P., Viguier M., Lesort C., Chaput B., Kanitakis J., Jullien D., Livideanu C. B., Lamant L., Pagès E., & Gaudenzio N. (2023).

April 2023 - Mast cell tolerance in the skin microenvironment to commensal bacteria is controlled by fibroblasts

Mast cell tolerance in the skin microenvironment to commensal bacteria is controlled by fibroblasts
Published in National Library of Medicine – April 28, 2023.
Anna Di Nardo, Yu-Ling Chang, Shahrzad Alimohammadi, Kana Masuda-Kuroki, Zhenping Wang, Krishna Sriram, Paul A Insel

March 2023 - Dissolvable microneedles for transdermal drug delivery showing skin penetration and modified drug release

Dissolvable microneedles for transdermal drug delivery showing skin penetration and modified drug release
Published in European Journal of Pharmaceutical Sciences (Volume 182, 1 March 2023, 106371) – March 1, 2023.
Irina Iachina, André H Eriksson, Malene Bertelsen, Karsten Petersson, Jörgen Jansson, Pernille Kemp, Karen M Engell, Jonathan R Brewer, Kim T Nielsen

March 2023 - A Needle-free Transdermal Patch for Sampling Interstitial Fluid

A Needle-free Transdermal Patch for Sampling Interstitial Fluid
Published in IEEE Transactions on Biomedical Engineering ( Volume: 70, Issue: 9, September 2023) – March 8, 2023.
D. J. O’Brien, D. Mills, J. Farina and M. Paranjape

February 2023 - Human filaggrin monomer does not seem to be a proteasome target

Human filaggrin monomer does not seem to be a proteasome target
Published in Experimental Dermatology – Volume 33, Issue 1 – February 20, 2023.
Julie Briot, Eric Arbey, Dominique Goudounèche, Dominique Bernard, Michel Simon, Marie-Claire Méchin

February 2023 - Topical Administration of Lactiplantibacillus plantarum (SkinDuoTM) Serum Improves Anti-Acne Properties

Topical Administration of Lactiplantibacillus plantarum (SkinDuoTM) Serum Improves Anti-Acne Properties
Published in MDPI – February 7, 2023.
Christine Podrini, Laetitia Schramm, Giulia Marianantoni, Jagienka Apolinarska, Colin McGuckin, Nico Forraz, Clément Milet, Anne-Laure Desroches, Pauline Payen, Maria D’Aguanno and Manuele Biazzo

January 2023 - An improved human skin explant culture method for testing and assessing personal care products

An improved human skin explant culture method for testing and assessing personal care products
Published in Journal of Cosmetic Dermatology – Volume 22, Issue 5 – January 6, 2023.
Linli Zhou PhD, Wei Ji MS, Teresa Dicolandrea PhD, Deborah Finlay PhD, Dorothy Supp PhD, Steven Boyce PhD, Karl Wei PhD, Ana Luisa Kadekaro PhD, Yuhang Zhang PhD

September 2022 - Transcriptome Analysis of Particulate Matter 2.5-Induced Abnormal Effects on Human Sebocytes

August 2022 - Immortalized human myoblast cell lines for the delivery of therapeutic proteins using encapsulated cell technology

May 2022 - Topical bioequivalence: Experimental and regulatory considerations following formulation complexity.

Topical bioequivalence: Experimental and regulatory considerations following formulation complexity.
Published in ScienceDirect – August, 2022. https://doi.org/10.1016/j.ijpharm.2022.121705.
Margarida Miranda, Cláudia Veloso, Marc Brown, Alberto A.C.C. Pais, Catarina Cardoso, Carla Vitorino

May 2022 - Mast cell–neuron axis in allergy

  • Mast cell–neuron axis in allergy 
    • Published in Current Opinion in Immunology – Volume 77, August 2022, 102213 – available online as of May 20, 2022
      • Nicolas Gaudenzio, Lilian Basso

January 2022 - Characterization of a novel non-steroidal glucocorticoid receptor agonist optimized for topical treatment

January 2022 - Polymethoxyflavones from Kaempferia parviflora ameliorate skin aging in primary human dermal fibroblasts and ex vivo human skin

December 2021 - Barrier disruption, dehydration and inflammation: Investigation of the vicious circle underlying dry skin

December 2021 - A hypothetical skin sensitisation next generation risk assessment for coumarin in cosmetic products

November 2021 - A suspended layer additive manufacturing approach to the bioprinting of tri-layered skin equivalents

October 2021 - The anti-wrinkles properties of sodium acetylated hyaluronate

October 2021 - A proof-of-concept study utilising 2D NMR spectrometry for in situ characterisation and quantitation of key biomarkers and actives in tape stripped ex vivo human skin

September 2021 - Clinical brightening efficacy and safety of Melasolv™ (3,4,5-trimethoxy cinnamate thymol ester, TCTE) in Southeast Asian women

July 2021 - Poster - Mitigation of Injection Site Reactions after Subcutaneous Administration of Dalcinonacog Alfa (DalcA) in Hemophilia B Using Preclinical Models

July 2021 - Poster - Assessing subcutaneous injection site reactions by leveraging immunocompetent human skin and artificial intelligence

March 2021 - Thesis - Development, validation and characterization of a perfused ex vivo human skin model : FlowSkin

February 2021 - hiPSC-Derived Epidermal Keratinocytes from Ichthyosis Patients Show Altered Expression of Cornification Markers

February 2021 - Calcipotriol/Betamethasone Dipropionate Foam Inhibits Th17 Cytokine Secretion and Improves Epidermal Barrier Markers in a Human Th17 Skin Inflammation Model

January 2021 - Challenges in Developing a Human Model System for Skin Microbiome Research

December 2020 - Active neutrophil responses counteract Candida albicans burn wound infection of ex vivo human skin explants

December 2020 - Standalone or combinatorial phenylbutyrate therapy shows excellent antiviral activity and mimics CREB3 silencing

December 2020 - Photothermally Active Cryogel Devices for Effective Release of Antimicrobial Peptides: On-Demand Treatment of Infections

November 2020 - Synthesis of Kisspeptin-Mimicking Fragments and Investigation of their Skin Anti-Aging Effects

October 2020 - Development and characterization of a human Th17 driven ex vivo skin inflammation model

October 2020 - Biomimetic and estrogenic fibers promote tissue repair in mice and human skin via estrogen receptor β

September 2020 - An ‘on-demand’ photothermal antibiotic release cryogel patch: evaluation of efficacy on an ex vivo model for skin wound infection

September 2020 - A novel skin brightening topical technology

  • A novel skin brightening topical technology
    • Published in Journal of Cosmetic Dermatology – 28 September 2020; 19: 3280– 3285
      • Zoe Diana Draelos MD, Isabel Diaz BA, Aaron Cohen PhD, Junhong Mao PhD, Thomas Boyd PhD

August 2020 - The anti-ageing effects of a natural peptide discovered by artificial intelligence

July 2020 - Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging

April 2020 - Identification of Malassezia furfur Secreted Aspartyl Protease 1 (MfSAP1) and Its Role in Extracellular Matrix Degradation

April 2020 - Single-cell transcriptomes of the human skin reveal age-related loss of fibroblast priming

April 2020 - Target-Site Penetration of Active Ingredients in Human Skin.

Target-Site Penetration of Active Ingredients in Human Skin.
Ph.D. Thesis published in Technische Universität Darmstadt – April, 2020. https://doi.org/10.25534/tuprints-00014169.
Markus Lubda.

January 2020 - Mapping 2D- and 3D-distributions of metal/metal oxide nanoparticles within cleared human ex vivo skin tissues

January 2020 - Epidermal and Dermal Hallmarks of Photoaging are Prevented by Treatment with Night Serum Containing Melatonin, Bakuchiol, and Ascorbyl Tetraisopalmitate: In Vitro and Ex Vivo Studies

January 2020 - Translational drug discovery and development with the use of tissue-relevant biomarkers: Towards more physiological relevance and better prediction of clinical efficacy

January 2020 - Anti-Wrinkle Benefits of Peptides Complex Stimulating Skin Basement Membrane Proteins Expression

Earlier Scientific Publications

2019 - An Efficient Means to Mitigate Skin Inflammaging by Inhibition of the NLRP3 Inflammasome and Nfkb Pathways: A Novel Epigenetic Mechanism

November 2019 - Sustained Secretion of the Antimicrobial Peptide S100A7 Is Dependent on the Downregulation of Caspase-8

October 2019 - Improvements of both inflammation and skin barrier in a human Th17 skin inflammation model by topical treatment with fixed-dose combination calcipotriene/betamethasone dipropionate foam

September 2019 - Peptidylarginine Deiminase Inhibitor Cl-Amidine Attenuates Cornification and Interferes with the Regulation of Autophagy in Reconstructed Human Epidermis

September 2019 - A human skin model to evaluate the protective effect of compounds against UVA damage

September 2019 - Poster - Scientific Visualisation of Skin Damage caused by Irritants in Human Skin

September 2019 - Poster - Evaluation of pharmacological responses to subcutaneous injection of adalimumab in InflammaSkin®, a full-thickness human ex vivo skin model reproducing key features of psoriatic lesions

September 2019 - Poster - Ex vivo visualization and extended release from a dissolvable microarray

  • Ex vivo visualization and extended release from a dissolvable microarray
    • Scientific Poster presented at the 2019 Congress of the European Society for Dermatological Research (ESDR) – September 18-21, 2019
      • K. T. Nielsen, A. H. Eriksson, M. F. Carlsen, K. M. Engel, J. Jansson, K. Petersson, M. A. Røpke, M. Bertelsen, P. Kemp –
        LEO Pharma A/S, Ballerup, Denmark

September 2019 - Poster - Preservation of human skin integrity and metabolism during 10 days in culture with NativeSkin® system

September 2019 - Poster - Bacterial infection and wound healing in an ex vivo human skin model

  • Bacterial infection and wound healing in an ex vivo human skin model
    • Scientific Poster presented at the 2019 Congress of the European Society for Dermatological Research (ESDR) – September 18-21, 2019
      • E. Pagès (Genoskin), M. Pastore (Genoskin), L. Rosselle (TissueAegis), A. Barras (UMR 8520 – IEMN), N. Skandrani (TissueAegis), A.R. Cantelmo (INSERM U1003), R. Boukherroub (UMR 8520 – IEMN), P. Descargues (Genoskin), S. Szunerits (UMR 8520 – IEMN)

August 2019 - Near-infrared light activable hydrogels for metformin delivery

  • Near-infrared light activable hydrogels for metformin delivery
    • Published in Nanoscale – 2019 Aug 29;11(34):15810-15820
      • Li Chengnan, Quentin Pagneux, Anna Voronova, Alexandre Barras, Amar Abderrahmani, Valérie Plaisance, Valerie Pawlowski, Nathalie Hennuyer, Bart Staels, Lea Rosselle, Nadia Skandrani, Musen Li, Rabah Boukherroub, Sabine Szunerits

July 2019 - The Actin-Based Motor Myosin Vb Is Crucial to Maintain Epidermal Barrier Integrity

June 2019 - The Amino-Terminal Part of Human FLG2 Is a Component of Cornified Envelopes

December 2018 - Melatonin, bakuchiol and ascorbyl tetraisopalmitate synergize to modulate gene expression and restore Hypoxia-Inducible Factor 1 signaling in UV-exposed skin

December 2018 - Poster - A fully functional ex vivo human skin model to study human skin microbiome

October 2018 - Phenotypic and lipidomic characterization of primary human epidermal keratinocytes exposed to simulated solar UV radiation

October 2018 - Myosin phosphatase accelerates cutaneous wound healing by regulating migration and differentiation of epidermal keratinocytes via Akt signaling pathway in human and murine skin

May 2018 - 3D imaging of cleared human skin biopsies using light-sheet microscopy: A new way to visualize in-depth skin structure

May 2018 - Poster - 3D imaging of cleared ex vivo normal human skin, skin appendages and psoriasiform skin lesion using light-sheet microscopy

May 2018 - Poster - NativeSkin®, an immunocompetent human skin model to study antigen uptake and processing by Langerhans cells

March 2018 - Poster - Epicutaneous immunotherapy with peanut directly tragets Langerhans cells in human skin

January 2018 - Poster - Evaluation of local inflammatory reactions following subcutaneous injection of a pro-inflammatory cocktail in a fully human ex vivo skin model

September 2017 - Oxidative damage and impairment of protein quality control systems in keratinocytes exposed to a volatile organic compounds cocktail

September 2017 - Poster - Evaluation of pharmacological responses in a fully human ex vivo skin model following in situ T cell activation with Th17/Th1 psoriasis-like phenotype

June 2017 - SIRT1 activation mediates heat-induced survival of UVB damaged Keratinocytes

January 2017 - Mechanistic insights into the impact of Cold Atmospheric Pressure Plasma on human epithelial cell lines

2016 - In vitro Dermal Absorption of Hydroquinone: Protocol Validation and Applicability on Illegal Skin-Whitening Cosmetics

November 2016 - Integrating targeted gene expression and a skin model system to identify functional inhibitors of the UV activated p38 MAP kinase

October 2016 - Thesis - Development of a human ex vivo melanoma model based on the implantation of tumor spheroids into skin explants

May 2016 - Heat-mediated reduction of apoptosis in UVB-damaged keratinocytes in vitro and in human skin ex vivo

October 2015 - In vitro and in vivo dermal absorption assessment of acetyl aspartic acid: a compartmental study

October 2015 - Safety assessment of a novel active ingredient, acetyl aspartic acid, according to the EU Cosmetics Regulation and the Scientific Committee on Consumer Safety guidelines

March 2015 - A Novel Explant Model for Skin Delivery Assessment

March 2015 - Human Skin Models for Research Applications in Pharmacology and Toxicology: Introducing NativeSkin®, the “Missing Link” Bridging Cell Culture and/or Reconstructed Skin Models and Human Clinical Testing

October 2014 - Calcipotriol counteracts betamethasone-induced decrease in extracellular matrix components related to skin atrophy

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