Human-based technology
for reliable results
Human data generation technologies to drive your research forward
Genoskin provides advanced human-based models designed to serve as ethical and scientifically robust alternatives to animal testing. These models offer more predictive and translatable solutions, enabling faster research progress and reducing the risks of failure, effectively bridging the gap between preclinical and clinical stages.
By utilizing donated, ethically sourced real human skin tissue, Genoskin develops innovative and reliable skin models. In addition to these advanced models, Genoskin supplies human primary mast cells for complementary in vitro testing. These solutions enable the efficient and reliable testing of chemical compounds, pharmaceuticals, cosmetic products, and medical devices without the need for animal testing.
Real human skin models
Preserving human skin viability is a key challenge in developing ex vivo models. Genoskin addresses this with standardized steps to rapidly biostabilize skin biopsies, maintaining an air-liquid interface and natural biomechanical properties. This process produces living, immunocompetent models that accelerate candidate selection in research.
Ethically sourced skin resections, primarily from abdominoplasties, are embedded in a solid gel-like matrix with a silicone ring to emulate natural tension. Cultured in a chemically defined, animal-free medium, these models remain viable for up to 10 days, providing accurate human data for research and development.
HypoSkin®:
Advancing subcutaneous injection research
HypoSkin® is a live ex vivo human skin model that includes the epidermis, dermis, and hypodermis layers, making it the first model on the market specifically designed for research on subcutaneous injection in human skin. Its versatility extends to studies involving other administration routes, such as transdermal application, intradermal injection, device insertion, and infusion, enabling broad research applications.
This model is ideal for efficacy and toxicity studies, providing key insights into immune responses and supporting therapeutic and vaccine development. HypoSkin® replicates human skin’s complexity, making it a valuable tool for preclinical evaluations.
HypoSkin®:
Advancing subcutaneous injection research
HypoSkin® is a live ex vivo human skin model that includes the epidermis, dermis, and hypodermis layers, making it the first model on the market specifically designed for research on subcutaneous injection in human skin. Its versatility extends to studies involving other administration routes, such as transdermal application, intradermal injection, device insertion, and infusion, enabling broad research applications.
This model is ideal for efficacy and toxicity studies, providing key insights into immune responses and supporting therapeutic and vaccine development. HypoSkin® replicates human skin’s complexity, making it a valuable tool for preclinical evaluations.
NativeSkin®:
Versatile models for diverse skin research applications
NativeSkin® is a live, immunocompetent ex vivo human skin model that preserves the natural architecture and functionality of real human epidermis and dermis for up to 10 days. By retaining the skin barrier, structural and immune cells, appendages, and donor-specific characteristics, the model provides a physiologically relevant platform for evaluating human skin response to topical and systemic compounds.
NativeSkin® supports efficacy, safety, absorption, irritation, inflammation, and barrier-function studies across pharmaceutical, cosmetic, chemical, and medical-device development, generating reproducible human data before clinical testing.
NativeSkin® Tape Stripped
A human skin model for barrier disruption and recovery studies
NativeSkin® Tape Stripped is a live, immunocompetent ex vivo human skin model with a mechanically altered skin barrier. While preserving the native epidermal and dermal architecture, structural cells, immune cells, and skin appendages, the model provides a controlled platform for investigating compromised barrier function, epidermal recovery, and topical delivery.
NativeSkin® Tape Stripped supports the evaluation of skincare formulations, dermatological treatments, and active ingredients designed to protect, restore, or penetrate the skin barrier, generating reproducible and human-relevant efficacy and safety data.
NativeSkin® Tape Stripped
A human skin model for barrier disruption and recovery studies
NativeSkin® Tape Stripped is a live, immunocompetent ex vivo human skin model with a mechanically altered skin barrier. While preserving the native epidermal and dermal architecture, structural cells, immune cells, and skin appendages, the model provides a controlled platform for investigating compromised barrier function, epidermal recovery, and topical delivery.
NativeSkin® Tape Stripped supports the evaluation of skincare formulations, dermatological treatments, and active ingredients designed to protect, restore, or penetrate the skin barrier, generating reproducible and human-relevant efficacy and safety data.
WoundSkin®:
A human ex vivo model for wound healing and infection research
WoundSkin® is a live, immunocompetent ex vivo human skin model featuring a standardized 2 mm wound. By reproducing key processes such as wound closure, re-epithelialization, bacterial colonization, and local immune responses, the model provides a controlled platform for studying tissue repair and wound infection.
WoundSkin® supports the evaluation of topical treatments, antimicrobial formulations, advanced dressings, and wound-care solutions in both preventive and therapeutic settings, generating reproducible, human-relevant data to guide preclinical development.
HairSkin®
A follicle-rich human skin model for hair and scalp research
HairSkin® is a live ex vivo human skin model derived from ethically sourced facelift tissue with a high density of mature hair follicles and pilosebaceous units. By preserving hair follicles, sebaceous glands, and immune cells, the model provides a physiologically relevant platform for studying hair follicle biology, sebum production, scalp health, and inflammatory responses.
HairSkin® supports the evaluation of haircare products, cosmetic ingredients, topical treatments, and therapeutic candidates, generating reproducible human data for efficacy, toxicity, and mechanistic studies.
HairSkin®
A follicle-rich human skin model for hair and scalp research
HairSkin® is a live ex vivo human skin model derived from ethically sourced facelift tissue with a high density of mature hair follicles and pilosebaceous units. By preserving hair follicles, sebaceous glands, and immune cells, the model provides a physiologically relevant platform for studying hair follicle biology, sebum production, scalp health, and inflammatory responses.
HairSkin® supports the evaluation of haircare products, cosmetic ingredients, topical treatments, and therapeutic candidates, generating reproducible human data for efficacy, toxicity, and mechanistic studies.
BreastSkin
A breast-specific ex vivo human skin model for cosmetic and dermatological research
BreastSkin is a live, full-thickness ex vivo human breast skin model derived from ethically sourced surgical discards. Built on Genoskin’s proven NativeSkin® biology, BreastSkin preserves real human tissue architecture and site-specific skin characteristics, making it ideal for studying breast, bust, décolleté, and sensitive-area skin care applications. This model supports topical product evaluation, active ingredient screening, and mechanistic claim substantiation for hydration, barrier function, skin smoothing, firmness-related pathways, extracellular matrix remodeling, oxidative stress protection, and anti-aging activity. By generating anatomically relevant human data before clinical testing, BreastSkin helps cosmetic, dermatology, and aesthetic R&D teams strengthen preclinical decision-making and support differentiated product development.
Human Mast Cells
Genoskin provides human primary mast cells for drug efficacy and toxicity testing, offering critical insights into immune responses and drug mechanisms. Using a proprietary process, mature mast cells are generated from healthy adult donors’ blood in one month, replicating the phenotype of connective tissue-type mast cells. These cells offer a reliable platform for studying immune mechanisms and testing therapeutic compounds in human-focused research.
Human Mast Cells
Genoskin provides human primary mast cells for drug efficacy and toxicity testing, offering critical insights into immune responses and drug mechanisms. Using a proprietary process, mature mast cells are generated from healthy adult donors’ blood in one month, replicating the phenotype of connective tissue-type mast cells. These cells offer a reliable platform for studying immune mechanisms and testing therapeutic compounds in human-focused research.