Alternatives to animal testing

Beyond animal models: The role of human skin in ADME testingADME (Absorption, Distribution, Metabolism, and Excretion) testing plays a vital role in modern drug development by improving candidate selection, reducing failures, enhancing safety assessments, ensuring regulatory compliance, and ultimately saving time and resources in bringing new drugs to market. Traditionally, ADME testing has relied on animal models and in vitroRead more

From human skin to human data: Advancing immunogenicity testing with human modelsIn a public workshop organized by the FDA-CRCG group, Dr. Nicolas Gaudenzio, CSO of Genoskin, introduced an innovative platform for assessing immune reactions in response to injected substances using human skin explants. His talk, titled "A new in vitro framework for assessing immunogenicity using comprehensive profiling of injectable humanRead more

HypoSkin services combine an ex vivo skin platform with new generation transcriptomic, cytokine analysis and bioinformatics to support your R&D with human insights.

The Silent Crisis in Biomedical Research: Beyond MacaquesFinding an alternative to non-human primates to evaluate human therapeutics In a compelling narrative echoed by Le Monde, the biomedical sector faces a silent crisis, highlighting the geopolitical intricacies and ethical quandaries of scientific research. At its core, the dwindling supply of non-human primates (NHPs), particularly macaques, essential for testing medical treatments, hasRead more

Top-level science through the eyes of an expert.The fifth Webinar. The fifth webinar in the Naked Immunology series is now scheduled on June 30, 2023 at 8 a.m. (PST), 11 a.m. (EST), 5 p.m. (CET). The webinar is open to English-speaking participants with a solid scientific background. Featured speaker is Dr. Cezmi Akdis, the director of the Swiss Institute ofRead more

Top differences between human and animal skin Are animal models used in skin research? Animal models have been widely used in skin research. They are often used to study percutaneous absorption, wound healing, skin inflammation and psoriasis. These studies require relevant models in terms of structure and immunology to assess human skin response and to de-risk clinical trials on humans. TheRead more