Human Skin

Advancing medical device development with ex vivo human skinMedical devices are evolving rapidly, becoming more sophisticated and diverse in their applications. From injectable drug delivery systems to wound dressings, wearable sensors, and microneedles, these innovations must undergo rigorous testing to ensure safety, functionality, and biocompatibility. However, as medical devices become more complex, so do the challenges associated with their preclinicalRead more

NativeSkin® & CosmeticsApplication NoteNativeSkin®: A Human Skin Model for Cosmetic Testing Discover NativeSkin®, an advanced ex vivo human skin model designed to provide a physiologically relevant and cruelty-free platform for cosmetic testing. This patented model preserves the structure, cellular complexity, and barrier function of real human skin, ensuring reliable assessments of efficacy (e.g., hydration, anti-aging, barrier repair) and safety (e.g.,Read more

From human skin to human data: Advancing immunogenicity testing with human modelsIn a public workshop organized by the FDA-CRCG group, Dr. Nicolas Gaudenzio, CSO of Genoskin, introduced an innovative platform for assessing immune reactions in response to injected substances using human skin explants. His talk, titled "A new in vitro framework for assessing immunogenicity using comprehensive profiling of injectable humanRead more

Top things found in human skin (vs in reconstructed human skin models) Covering nearly two square meters, skin is our body’s largest organ and a common pathway for administering drugs—whether through topical applications, subcutaneous injections, intradermal routes, or medical devices. With its complex network of immune cells, the skin plays an essential role in testing the efficacy and safety ofRead more

This application note highlights new comparative data on T cell dynamics in HypoSkin^® and InflammaSkin^®, generated using flow cytometric analysis.

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