Toxicity

26
Jun

Understanding neurogenic inflammation

Understanding Pain & Neurogenic InflammationCan our understanding of pain and neurogenic inflammation help in predicting and managing injection-related pain?Nociception, the neural processes of encoding and processing noxious stimuli, and the sensation of pain are initiated by extreme pressures, temperatures, toxic substances, and inflammatory mediators capable of causing tissue injury. These strong stimuli are recognized by specific nerve cells in the
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12
Jun

CASE STUDY – Cetrorelix & ISR

Discover how the ImmunoSafe: ISR Platform® support the evaluation of local immune reactions caused by subcutaneous administration of Cetrorelix.

12
Jun

APPLICATION NOTE – ISR

Explore how the ISR Platform® can effectively de-risk your injectable therapeutic candidates today!

12
Jun

APPLICATION NOTE – Non clinical toxicity services

Discover a quick approach to de-risk your injectable therapeutic candidates using ex vivo live human skin.

16
May

Injection site reactions platform

Assessment of injection site reactionsA new proprietary research tool to identify drug-related immune adverse reactions in human skinToday, biologics represent one of the fastest growing markets within the pharmaceutical industry.The pipeline of biological drugs is growing at a rapid pace with a global market expected to reach over 460 billion USD in 2024 (1). In order to bypass gastric metabolism,
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2
May

Unwanted immunogenicity

Navigating Unwanted ImmunogenicityPart 3 - Challenges & insights in biologic drug developmentOver the past two and a half decades, biologics development has been growing exponentially, matching the pace of small molecules development in 20221. Biologics, or biopharmaceutical products, encompass a wide range of therapeutic products such as vaccines, monoclonal antibodies, gene and cell therapy, and recombinant and fusion therapeutic proteins.
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