Toxicity

Home / Resources / Posters Poster Improving Clinical Translation Through Human Skin-Based New Approach Methodologies Adeline Chaubet1, Mathias Peries1, Mamoudou Diallo1, Laurianne Kandalaft1, Anthony David1, Emeline Pagès1, Nicolas Gaudenzio1,2 1Genoskin SAS, Toulouse, France & 2University of Toulouse, Inserm, CNRS, Toulouse Institute for Infectious and Inflammatory Diseases (Infinity), Toulouse, France. Advancing drug development with New Approach Methodologies (NAMs) Accurate prediction ofRead more

Home / Resources / Posters Poster Replacing animal testing in local tolerance assessment of an injection device: Human ex vivo HypoSkin® model as a New Approach Methodology (NAM) Jérémy Argenty1, Clémence Letzelter1, Catherine Marques1, Sophie Abadie1, Alexia Sanchez1, Claire Gendrin1, Alexandra Ochando1, Adam Rock2, Ronan Byrne2, Pascal Descargues1 and Nicky Bertollo2 1Genoskin, 2Pharma Latch HypoSkin® is an ex vivo human skin NAM thatRead more

Home / Resources / Posters Poster HypoSkin® as a human-based NAMs platform for local toxicity and formulation safety assessment Julie Magerman1, Katarzyna Polak2, Ornella Binazon1, Michael Pastore2, Alexandra Ochando2 and Judith Baumeister1 1argenx, 2Genoskin Local Toxicity and Formulation Safety: An argenx Collaboration Study Formulation safety testing still relies heavily on in vivo studies due to limited validated in vitro alternatives. Genoskin’s HypoSkin® biostabilized ex vivo human skinRead more

Download this application note and discover 3 case studies. Refine formulations or assess local tolerance in human skin before clinical trials.

Explore how HypoSkin®—a standardized, injectable, and immunocompetent human skin model—provides a translational, animal-free solution for assessing the immunogenicity of therapeutic compounds. From structural stability to real-time immune response profiling, this white paper delivers data-backed insights designed for pharma and biotech teams advancing injectable drug development.

Top-level science through the eyes of an expert.Join us for the next session in Genoskin’s webinar series, where we explore cutting-edge advancements in drug delivery and therapeutic innovation. This session will feature an in-depth presentation on polymer prodrug nanocarriers, showcasing a novel approach to controlled and efficient drug release. Watch the replayThis webinar explores new research on polymer-drug conjugates inRead more