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NativeSkin® & PharmaApplication NoteNativeSkin®: a human skin model for pharma applications Discover NativeSkin®, an advanced ex vivo human skin model designed to provide a physiologically relevant, cruelty-free platform for pharmaceutical research. This patented model preserves the structure, cellular complexity, and barrier function of real human skin, enabling reliable assessments of drug efficacy (e.g., transdermal delivery, topical activity, anti-inflammatory effects) andRead more

Vaccine DevelopmentVaxSkin® an innovative platform to study vaccine immunogenicityIntroduction The field of drug development is witnessing a remarkable surge in the development of innovative strategies. There is a need to develop technological platforms capable of generating human data prior to progressing to clinical trials. Developing safe and effective vaccines requires a clear understanding of early immune responses at the injectionRead more

Advancing medical device development with ex vivo human skinMedical devices are evolving rapidly, becoming more sophisticated and diverse in their applications. From injectable drug delivery systems to wound dressings, wearable sensors, and microneedles, these innovations must undergo rigorous testing to ensure safety, functionality, and biocompatibility. However, as medical devices become more complex, so do the challenges associated with their preclinicalRead more

NativeSkin® & CosmeticsApplication NoteNativeSkin®: A Human Skin Model for Cosmetic Testing Discover NativeSkin®, an advanced ex vivo human skin model designed to provide a physiologically relevant and cruelty-free platform for cosmetic testing. This patented model preserves the structure, cellular complexity, and barrier function of real human skin, ensuring reliable assessments of efficacy (e.g., hydration, anti-aging, barrier repair) and safety (e.g.,Read more

Beyond animal models: The role of human skin in ADME testingADME (Absorption, Distribution, Metabolism, and Excretion) testing plays a vital role in modern drug development by improving candidate selection, reducing failures, enhancing safety assessments, ensuring regulatory compliance, and ultimately saving time and resources in bringing new drugs to market. Traditionally, ADME testing has relied on animal models and in vitroRead more

The future of vaccine researchThe rapid advancements in vaccine research over the past decade have transformed the way we prevent and respond to infectious diseases. The COVID-19 pandemic accelerated the development of novel platforms like mRNA vaccines, showcasing the potential for rapid innovation. However, despite these breakthroughs, significant challenges remain in vaccine research, including preclinical model limitations, immune variability, theRead more