Skin Models

This application note highlights new comparative data on T cell dynamics in HypoSkin® and InflammaSkin®, generated using flow cytometric analysis.

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In this white paper, discover new validation data demonstrating the stability, injectability and immunocompetency of our HypoSkin model.

Skin MicrobiomeA fully functional ex vivo human skin model to study human skin microbiome Research by B. Coupe1, M. Pastore2, E. Pagès2, E. Braun2, A. Broha1, P. Descargues2 1Vaiomer, 2Genoskin The human skin is colonized by a diverse population of microorganisms. The symbiotic host-microorganism relationship can be affected by numerous endogenous and exogenous factors. This can result in skin disordersRead more

Skin ModelsPreservation of human skin integrity and metabolism during 10 days in culture with NativeSkin® system Research by E. Raude1, E. Pagès1, M. Pastore1, P.-O. Cuoc2, L. Malaquin3, P. Descargues1 1Genoskin, 2Promega, 3LAAS-CNRS Scientific Context Human epidermis is not vascularized and oxygen only reaches epidermal cells by diffusing through the stratum corneum or from the dermal papillae which contains aRead more

Skin ModelsNativeSkin®, an immunocompetent human skin model to study antigen uptake and processing by Langerhans cells Research by E. Pagès1, L. Mondoulet3, E. Bonnefont1, E. Braun1, V. Dhelft2, C. Dupont3, H. Sampson2, P. Descargues1 1Genoskin, 2DBV Technologies, 3Hôpital Necker, Université Paris-Descartes Scientific Context Epicutaneous immunotherapy (EPIT) using Viaskin® patches has been shown to induce tolerance in sensitized mice (Dioszeghy, ClinRead more