Skin Models

Explore how HypoSkin®—a standardized, injectable, and immunocompetent human skin model—provides a translational, animal-free solution for assessing the immunogenicity of therapeutic compounds. From structural stability to real-time immune response profiling, this white paper delivers data-backed insights designed for pharma and biotech teams advancing injectable drug development.

NativeSkin® & PharmaApplication NoteNativeSkin®: a human skin model for pharma applications Discover NativeSkin®, an advanced ex vivo human skin model designed to provide a physiologically relevant, cruelty-free platform for pharmaceutical research. This patented model preserves the structure, cellular complexity, and barrier function of real human skin, enabling reliable assessments of drug efficacy (e.g., transdermal delivery, topical activity, anti-inflammatory effects) andRead more

Advancing medical device development with ex vivo human skinMedical devices are evolving rapidly, becoming more sophisticated and diverse in their applications. From injectable drug delivery systems to wound dressings, wearable sensors, and microneedles, these innovations must undergo rigorous testing to ensure safety, functionality, and biocompatibility. However, as medical devices become more complex, so do the challenges associated with their preclinicalRead more

NativeSkin® & CosmeticsApplication NoteNativeSkin®: A Human Skin Model for Cosmetic Testing Discover NativeSkin®, an advanced ex vivo human skin model designed to provide a physiologically relevant and cruelty-free platform for cosmetic testing. This patented model preserves the structure, cellular complexity, and barrier function of real human skin, ensuring reliable assessments of efficacy (e.g., hydration, anti-aging, barrier repair) and safety (e.g.,Read more

Beyond animal models: The role of human skin in ADME testingADME (Absorption, Distribution, Metabolism, and Excretion) testing plays a vital role in modern drug development by improving candidate selection, reducing failures, enhancing safety assessments, ensuring regulatory compliance, and ultimately saving time and resources in bringing new drugs to market. Traditionally, ADME testing has relied on animal models and in vitroRead more

HairSkin®Human skin model with hair folliclesHairSkin®: the first ex vivo human skin model with mature pilosebaceous units HairSkin® is a cutting-edge ex vivo human skin model, developed with tissue containing fully mature pilosebaceous units. HairSkin® is designed to meet the requirements of both pharmaceutical and cosmetic industries and to empower innovation in dermatology, cosmetics, and personal care. Thanks to aRead more