Skin Models

Download this application note and discover 3 case studies. Refine formulations or assess local tolerance in human skin before clinical trials.

Prove ADCC Activity in Real Human Skin For therapies targeting mast cells, demonstrating antibody-dependent cell-mediated cytotoxicity (ADCC) in complex human tissue is essential. Traditional in vitro assays provide limited context, leaving critical aspects of biological impact unclear. HypoSkin® offers a solution Our ex vivo human skin model lets you assess mast cell depletion in situ, offering a powerful, human-relevant platformRead more

Explore how HypoSkin®—a standardized, injectable, and immunocompetent human skin model—provides a translational, animal-free solution for assessing the immunogenicity of therapeutic compounds. From structural stability to real-time immune response profiling, this white paper delivers data-backed insights designed for pharma and biotech teams advancing injectable drug development.

NativeSkin® & PharmaApplication NoteNativeSkin®: a human skin model for pharma applications Discover NativeSkin®, an advanced ex vivo human skin model designed to provide a physiologically relevant, cruelty-free platform for pharmaceutical research. This patented model preserves the structure, cellular complexity, and barrier function of real human skin, enabling reliable assessments of drug efficacy (e.g., transdermal delivery, topical activity, anti-inflammatory effects) andRead more

Advancing medical device development with ex vivo human skinMedical devices are evolving rapidly, becoming more sophisticated and diverse in their applications. From injectable drug delivery systems to wound dressings, wearable sensors, and microneedles, these innovations must undergo rigorous testing to ensure safety, functionality, and biocompatibility. However, as medical devices become more complex, so do the challenges associated with their preclinicalRead more

NativeSkin® & CosmeticsApplication NoteNativeSkin®: A Human Skin Model for Cosmetic Testing Discover NativeSkin®, an advanced ex vivo human skin model designed to provide a physiologically relevant and cruelty-free platform for cosmetic testing. This patented model preserves the structure, cellular complexity, and barrier function of real human skin, ensuring reliable assessments of efficacy (e.g., hydration, anti-aging, barrier repair) and safety (e.g.,Read more