Cosmetic claim substantiation

Innovative cosmetic efficacy studies

A new approach to cosmetic claim substantiation

Without harming humans or animals

Genoskin uses an innovative approach to help the cosmetic and aesthetic industry substantiate their claims and assess the efficacy and safety of cosmetic ingredients and injectables without harming either humans or animals. We combine live human skin platforms and expert tools to deliver cosmetic and aesthetic efficacy studies with high-quality results in order to substantiate your claims.

Animal-free

Our unique human data generation platforms provide a reliable alternative to animal testing, using real, live human skin.

Cosmetic Claim

Our skin platforms are suitable for a wide range of compounds requiring topical, systemic or intradermal administration, e.g. fillers.

Testing

Our platforms allow to study your compound on different donors to reflect the diversity of your target group and the human population.

Platform

We provide a unique view into efficacy, cellular regeneration, longevity,… thanks to our dedicated Mantis® spatial biology platform.

Cosmetic claim substantiation

A crucial element in cosmetic marketing

Even though cosmetic products are not subject to specific market authorisations, they still need to comply with certain regulations. Claim substantiation is crucial for consumers to differentiate products and make informed decisions. However, all claims must be substantiated by scientifically solid, reliable and reproducible studies that follow a well-designed methodology in order to protect end-users.

Source: https://ec.europa.eu/docsroom/documents/24847

Nativeskin human skin model close-up

Efficacy studies for cosmetic ingredients

Test your compounds on live human skin

When it comes to cosmetic claim substantiation, NativeSkin® is our most popular data generation platform. NativeSkin® is real, donated human skin that is kept alive for 7 days thanks to our unique technology. This approach allows you to test your compounds on real human skin while observing live human skin response for an entire week. And all of this, without harming either humans or animals. Our NativeSkin access® skin models are available for shipment worldwide.

More about NativeSkin® Models

A reliable alternative to animal testing

An animal-free & xeno-free approach

Due to increased awareness on the fate of laboratory animals, more and more countries are banning animal testing for cosmetic ingredients and products. In the EU, testing cosmetics on animals has been banned since 2009. Since 2013, it is even illegal to put cosmetics that were tested on animals on the European market. To date, 41 countries have passed laws to limit or completely ban animal testing for cosmetics, including all EU-countries, the UK, Australia, Mexico and India. Some US states, such as California, Hawaii, Illinois, Maine, Maryland, Nevada, New Jersey and Virginia have already followed suit and more are likely to follow. Since animal skin differs from human skin, Genoskin’s human data generation platforms do not only provide an excellent alternative to animal testing, our solution also provides more reliable data on the compounds you test.

Source: https://www.humanesociety.org/resources/cosmetics-testing-faq

Innovative solutions for innovative cosmetics

Reliable data for all types of cosmetic ingredients & compounds

Constant adaptation and innovation are key to the cosmetic industry in order to meet market and customer expectations. To cater to the needs of all cosmetic companies, Genoskin not only offers skin models for compounds and ingredients that require topical or systemic application, we’re the only company in the world that provides live human skin platforms to test response to subcutaneous injection. To this effect, we use our Hyposkin® model, which, in addition to the live human dermis and epidermis contained in NativeSkin®, also includes human adipose tissue to make it suitable for subcutaneous and intradermal testing. However, our model for subcutaneous injection is only available as an in-house service for custom studies.

Topical application

Subcutaneous-injections-300x300

Subcutaneous injection

Systemic administration

Study efficacy for multiple donors

Include donor diversity to increase data relevance

Since our human data generation platforms only contain donated skin, it is possible to conduct studies on multiple donors to represent the diversity of the human population or of your target audience. The characteristics of our skin models are donor-dependent and are one of the great strengths of our approach. They reflect natural biological diversity in the general population, allowing for more accurate and relevant study results.

Variety of donors for psoriasis studies

Substantiate all your cosmetic claims

A quick overview of the studies we can conduct for you

Over the years, Genoskin has acquired unique expertise in skin biology and immunology and helped numerous customers obtain the results they need. Below you’ll find a quick overview of the studies we conduct routinely in our lab. Should you be looking for something that is not listed, don’t hesitate to get in touch so we can help you design the perfect study to substantiate your claim.

Effects on skin metabolism

Examples of scientific publications

Below you’ll find some examples of scientific publications on this topic that refer to our products and/or services. Don’t hesitate to contact us for more information.

Skin brightening & whitening

Examples of scientific publications

Below you’ll find some examples of scientific publications on this topic that refer to our products and/or services. Don’t hesitate to contact us for more information.

Skin microbiome

Examples of scientific publications

Below you’ll find some examples of scientific publications on this topic that refer to our products and/or services. Don’t hesitate to contact us for more information.

Skin plumping

Skin regeneration

Not sure what study would work best? Let us help you out!

The Genoskin team has over 10 years of experience in skin biology and immunology. We’re more than happy to help you select the right skin platform and study set-up to obtain the results you need. Don’t hesitate to get in touch!