HypoSkin®
A structurally stable, injectable & immunocompetent human skin model
HypoSkin® – A structurally stable, injectable, and immunocompetent human skin model
HypoSkin® is a living, immunocompetent ex vivo human skin model that preserves all three skin layers, including the hypodermis. Designed for intradermal and subcutaneous injections, it provides a human-relevant platform for investigating injectable therapeutics, local tissue tolerance, and immune responses.
This white paper presents experimental validation of HypoSkin®, demonstrating structural preservation over 7 days, successful intradermal and subcutaneous injections, and characterization of cellular populations and transcriptomic stability during culture.
Using histology, two-photon imaging, X-ray tomography, and single-cell RNA sequencing, the study provides evidence supporting the model’s suitability for preclinical research.
Download the white paper to explore the validation data and learn how HypoSkin® can support your injectable drug development studies.
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