Intradermal device testing

Jérémy Argenty¹, Clémence Letzelter¹, Catherine Marques¹, Sophie Abadie¹, Alexia Sanchez¹, Claire Gendrin¹, Alexandra Ochando¹, Adam Rock², Ronan Byrne², Pascal Descargues¹, Nicky Bertollo^2
1Genoskin, ²Pharma Latch

HypoSkin^® is an ex vivo human skin NAM that preserves native immune cells and tissue architecture for local tolerance testing. Using a customized workflow, we compared an innovative fixed-depth intradermal device with a 30G syringe and reference device. All injections were well tolerated, with preserved histology and only mild, physiological cytokine responses, including comparable vaccine-induced activation.

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