T Cell Activation in InflammaSkin^®

This application note highlights new comparative data on T cell dynamics in HypoSkin^® and InflammaSkin^®, generated using flow cytometric analysis. The analysis reveals increased expression of activation marker CD69 and proliferation marker Ki-67, along with differences in CD8+ and CD4+ T cell populations and the presence of double-positive T cells. These findings emphasize InflammaSkin’s ability to replicate an inflammatory environment characteristic of psoriasis, offering a robust platform for evaluating T cell-mediated immune responses and potential therapeutic interventions.