Blog

Rethinking wound healing: from classical readouts to emerging ways of studying tissue repairEvery day, our skin quietly repairs itself after injury, a process that relies on a complex regenerative program. In this blog, we explore what drives effective wound repair, why some wounds fail to heal, and what it takes to translate laboratory insights into meaningful clinical outcomes.Wound healing: biologicalRead more

Integrating microbiome sciencewith cosmetic product developmentBeyond clean claims, the emergence of skin microbiome in skin careSkin care is entering a new era, one where skin biology, consumer insight, and smart formulation converge to shape innovation. At the center of this shift, the skin microbiome has emerged as a key focus, opening new pathways for cosmetic testing and research, driving theRead more

Advancing medical device development with ex vivo human skinMedical devices are evolving rapidly, becoming more sophisticated and diverse in their applications. From injectable drug delivery systems to wound dressings, wearable sensors, and microneedles, these innovations must undergo rigorous testing to ensure safety, functionality, and biocompatibility. However, as medical devices become more complex, so do the challenges associated with their preclinicalRead more

Beyond animal models: The role of human skin in ADME testingADME (Absorption, Distribution, Metabolism, and Excretion) testing plays a vital role in modern drug development by improving candidate selection, reducing failures, enhancing safety assessments, ensuring regulatory compliance, and ultimately saving time and resources in bringing new drugs to market. Traditionally, ADME testing has relied on animal models and in vitroRead more

The future of vaccine researchThe rapid advancements in vaccine research over the past decade have transformed the way we prevent and respond to infectious diseases. The COVID-19 pandemic accelerated the development of novel platforms like mRNA vaccines, showcasing the potential for rapid innovation. However, despite these breakthroughs, significant challenges remain in vaccine research, including preclinical model limitations, immune variability, theRead more

From human skin to human data: Advancing immunogenicity testing with human modelsIn a public workshop organized by the FDA-CRCG group, Dr. Nicolas Gaudenzio, CSO of Genoskin, introduced an innovative platform for assessing immune reactions in response to injected substances using human skin explants. His talk, titled "A new in vitro framework for assessing immunogenicity using comprehensive profiling of injectable humanRead more