Resources

Injection-Site PainWhich factors influence pain upon subcutaneous injection?Biologics such as vaccines, insulin, monoclonal antibodies, etc., that are now widely developed need to be administered parenterally. While the intravenous (IV) route has historically been the most widely used,  the subcutaneous (SC) route is now accepted and presented as safe and effective, whether in the context of chronic disease or in palliativeRead more

Immunogenicity SeriesPart 4 - Evaluating and managing immunogenicity for vaccinesImmunogenicity is crucial in vaccine development, it represents the capacity of a substance, such as a vaccine, to elicit an immune response. This reaction can be beneficial, providing protection against diseases, or detrimental, resulting in adverse effects. In vaccine development, the goal is to trigger on-target immunogenicity to activate the immuneRead more

HypoSkin®, an ex vivo human skin model to predict toxicity & efficacy of subcutaneous drugs Recent advancements in subcutaneous injection testing have brought about significant improvements in drug delivery and patient experience. These advancements include the development of innovative injection devices and formulations that enhance the ease and comfort of subcutaneous drug administration. Market trends also indicate a growing demandRead more

ProtocolSubcutaneous InjectionSubcutaneous injection protocol for HypoSkin® Genoskin’s subcutaneous injection protocol provides step-by-step guidance for administering test compounds into the hypodermis of our HypoSkin® ex vivo human skin model. Developed by our scientific team, this protocol supports consistent and reproducible injections for evaluating injectable drugs, formulations, and their local effects on human skin tissue. Please fill in the form below toRead more

ProtocolIntradermal InjectionIntradermal injection protocol for HypoSkin® Genoskin’s intradermal injection protocol is designed to support accurate and reproducible administration of test compounds into our HypoSkin® ex vivo human skin model. Developed by our scientific teams, this protocol provides practical guidance for performing intradermal injections while preserving tissue integrity and ensuring consistency across experiments. Please fill in the form below to accessRead more

HypoSkin services combine an ex vivo skin platform with new generation transcriptomic, cytokine analysis and bioinformatics to support your R&D with human insights.