Resources

Transforming Drug SafetyThe Revolutionary Role of Investigative Toxicology in Drug DevelopmentIn an era where the pace of pharmaceutical innovation is rapidly evolving, the field of toxicology is undergoing a transformative shift. This goes beyond subtle changes; there is a fundamental reimagining of its role from observing drug-induced effects to proactively shaping drug safety measures.The Integration of Investigative Toxicology The traditionalRead more

Top-level science through the eyes of an expert.The seventh Webinar. The seventh webinar in the Naked Immunology series is now scheduled on April 8, 2024 at 8 a.m. (PST), 11 a.m. (EST), 5 p.m. (CET). The webinar is open to English-speaking participants with a solid scientific background. Featured speaker is Dr. Marcus Maurer, MD, Professor of Dermatology and Allergy, Co‐DirectorRead more

The Silent Crisis in Biomedical Research: Beyond MacaquesFinding an alternative to non-human primates to evaluate human therapeutics In a compelling narrative echoed by Le Monde, the biomedical sector faces a silent crisis, highlighting the geopolitical intricacies and ethical quandaries of scientific research. At its core, the dwindling supply of non-human primates (NHPs), particularly macaques, essential for testing medical treatments, hasRead more

Immunogenicity SeriesPart 2 - Wanted Immunogenicity for Vaccine DevelopmentImmunogenicity is a key concept in vaccine development,referring to the ability of a vaccine to stimulate an immune response in the recipient. It is a desirable and critical characteristic because the effectiveness of a vaccine is directly linked to its ability to induce a robust and protective immune response. Vaccine Development: GlobalRead more

Understanding Local Tolerancein Drug DevelopmentIn the ever-evolving field of drug development, ensuring the safety and efficacy of new therapeutic agents is paramount. A crucial aspect of this safety evaluation is the assessment of cytotoxicity – the potential of substances to harm or destroy cells. Particularly in the realm of skin cytotoxicity, the concept of Local Tolerance, especially in the contextRead more

Immunogenicity SeriesPart 1 - Defining immunogenicity Immunogenicity plays a pivotal role in drug and vaccine development and is essential for optimizing therapeutic efficacy and safetyby understanding the immune system's response to the compounds being tested. This is particularly crucial in the era of biologics and personalized medicine, where the fine balance between therapeutic benefit and immune reactivity is critical. WhetherRead more