Injectables

Beyond animal models: The role of human skin in ADME testingADME (Absorption, Distribution, Metabolism, and Excretion) testing plays a vital role in modern drug development by improving candidate selection, reducing failures, enhancing safety assessments, ensuring regulatory compliance, and ultimately saving time and resources in bringing new drugs to market. Traditionally, ADME testing has relied on animal models and in vitroRead more

Top-level science through the eyes of an expert.Join us for the next session in Genoskin’s webinar series, where we explore cutting-edge advancements in drug delivery and therapeutic innovation. This session will feature an in-depth presentation on polymer prodrug nanocarriers, showcasing a novel approach to controlled and efficient drug release. Watch the replayThis webinar explores new research on polymer-drug conjugates inRead more

From human skin to human data: Advancing immunogenicity testing with human modelsIn a public workshop organized by the FDA-CRCG group, Dr. Nicolas Gaudenzio, CSO of Genoskin, introduced an innovative platform for assessing immune reactions in response to injected substances using human skin explants. His talk, titled "A new in vitro framework for assessing immunogenicity using comprehensive profiling of injectable humanRead more

The landscape of vaccine research is undergoing an important transformation, thanks to the breakthroughs in mRNA vaccine technology.

In this white paper, discover new validation data demonstrating the stability, injectability and immunocompetency of our HypoSkin^® model.

Mast CellsSingle-cell profiling of biostabilized natural human skin identifies mast cells as an important target of injected mRNA-1273 COVID-19 vaccine. Research by M. Scholaert1,2, M. Peries2, E. Braun2, J. Martin1, N. Serhan1, A. Loste1, A. Bruner1, L. Basso1, E. Merle2, A. Trevisiol2, E. Pagès2 and N. Gaudenzio1,2 1Toulouse Insitute for Infectious and Inflammatory Diseases (Infinity), 2Genoskin Single-cell profiling reveals mastRead more