Injectables

Top-level science through the eyes of an expert.Preclinical evaluation of an energy-driven device for localized skin delivery of nucleic acidsDid you miss the live session? The full webinar recording is now available to watch on demand. Explore preclinical insights into an energy-driven, microneedle-based device enabling localized, non-viral delivery of naked nucleic acids to skin, highlighting transgene expression, immune activation, andRead more

Download this application note and discover 3 case studies. Refine formulations or assess local tolerance in human skin before clinical trials.

Prove ADCC Activityin real human skinFor therapies targeting mast cells, demonstrating antibody-dependent cell-mediated cytotoxicity (ADCC) in complex human tissue is essential.Traditional in vitro assays provide limited context, leaving critical aspects of biological impact unclear. HypoSkin® offers a solution Our ex vivo human skin model lets you assess mast cell depletion in situ, offering a powerful, human-relevant platform to confirm theRead more

Explore how HypoSkin®—a standardized, injectable, and immunocompetent human skin model—provides a translational, animal-free solution for assessing the immunogenicity of therapeutic compounds. From structural stability to real-time immune response profiling, this white paper delivers data-backed insights designed for pharma and biotech teams advancing injectable drug development.

Vaccine DevelopmentVaxSkin® an innovative platform to study vaccine immunogenicityUnlocking vaccine immunogenicity insights with VaxSkin® Understanding early immune responses to vaccination is essential for developing safe and effective vaccines. However, conventional preclinical models often struggle to reproduce the complexity of human skin immunity, particularly the interactions between resident immune cells at the injection site. In this application note, we explore howRead more

Advancing medical device development with ex vivo human skinMedical devices are evolving rapidly, becoming more sophisticated and diverse in their applications. From injectable drug delivery systems to wound dressings, wearable sensors, and microneedles, these innovations must undergo rigorous testing to ensure safety, functionality, and biocompatibility. However, as medical devices become more complex, so do the challenges associated with their preclinicalRead more