Toxicology

Top-level science through the eyes of an expert.Join us for the next session in Genoskin’s webinar series, where we explore cutting-edge advancements in drug delivery and therapeutic innovation. This session will feature an in-depth presentation on polymer prodrug nanocarriers, showcasing a novel approach to controlled and efficient drug release. Watch the replayThis webinar explores new research on polymer-drug conjugates inRead more

Genoskin at the SOT 64th Annual Meeting and ToxExpoAdvancing non-clinical toxicity assessment with ex vivo human skin and mast cell models We are excited to participate in the SOT 64th Annual Meeting and ToxExpo, taking place from March 16-20, 2025, at the Orange County Convention Center in Orlando, Florida. As one of the most influential events in toxicology, this meetingRead more

From human skin to human data: Advancing immunogenicity testing with human modelsIn a public workshop organized by the FDA-CRCG group, Dr. Nicolas Gaudenzio, CSO of Genoskin, introduced an innovative platform for assessing immune reactions in response to injected substances using human skin explants. His talk, titled "A new in vitro framework for assessing immunogenicity using comprehensive profiling of injectable humanRead more

Discover how the ImmunoSafe: ISR Platform^® support the evaluation of local immune reactions caused by subcutaneous administration of Cetrorelix.

Scientific posterDecoding Injection Site Reactogenicity & Immunotoxicity: A Novel Approach Integrating Human Skin Models with Secretome & Pathway Analytics.There is growing interest in the subcutaneous (SC) route of injection among patients, allowing for slow and sustained release of therapeutic molecules into the bloodstream. This approach empowers patients to self-administer treatment at home. However, the majority of biologics are associated withRead more

Assessment of injection site reactionsA new proprietary research tool to identify drug-related immune adverse reactions in human skinToday, biologics represent one of the fastest growing markets within the pharmaceutical industry.The pipeline of biological drugs is growing at a rapid pace with a global market expected to reach over 460 billion USD in 2024 (1). In order to bypass gastric metabolism,Read more