Overview of scientific publications
Examples of how our Models & Services can be used
Publications in scientific journals & magazines
Most Recent Scientific Publications
Genoskin aims to change drug development as we know it by using cutting-edge technology to make science move forward. Below you’ll find a list of publications that validate and/or use our unique technology and skin models for a wide range of applications. Simply click on the + sign to obtain more details and to access the publication of your choice.
August 2023 - M1/M2 Macrophage Skewing is Related to Reduction in Type I, V and VI Collagens with Aging in Sun-exposed Human Skin.
M1/M2 Macrophage Skewing is Related to Reduction in Type I, V and VI Collagens with Aging in Sun-exposed Human Skin.
Published in JID Innovations, 2023, 100222, ISSN 2667-0267 – August 11, 2023.
Satoshi Horiba, Munetaka Kawamoto, Ryozo Tobita, Ryota Kami, Yuki Ogura, Junichi Hosoi
Published in JID Innovations, 2023, 100222, ISSN 2667-0267 – August 11, 2023.
Satoshi Horiba, Munetaka Kawamoto, Ryozo Tobita, Ryota Kami, Yuki Ogura, Junichi Hosoi
August 2023 - Evaluating the Impact of Hair Care Product Exposure on Hair Follicle and Scalp Health
Evaluating the Impact of Hair Care Product Exposure on Hair Follicle and Scalp Health.
Published in Alternatives to Laboratory Animals (ATLA) – 2023;0(0).
Fung ES, Parker JA, Monnot AD.
Published in Alternatives to Laboratory Animals (ATLA) – 2023;0(0).
Fung ES, Parker JA, Monnot AD.
August 2023 - Hydrogel degradation promotes angiogenic and regenerative potential of cell spheroids for wound healing
Hydrogel degradation promotes angiogenic and regenerative potential of cell spheroids for wound healing.
Published in Materials Today Bio – Volume 22, 2023,100769, ISSN 2590-0064; Published: 29 September 2022.
Victoria L. Thai, David H. Ramos-Rodriguez, Meron Mesfin, J. Kent Leach.
Published in Materials Today Bio – Volume 22, 2023,100769, ISSN 2590-0064; Published: 29 September 2022.
Victoria L. Thai, David H. Ramos-Rodriguez, Meron Mesfin, J. Kent Leach.
July 2023 - Engineering a versatile and retrievable cell macroencapsulation device for the delivery of therapeutic proteins.
Engineering a versatile and retrievable cell macroencapsulation device for the delivery of therapeutic proteins.
Published in iScience, Volume 26, Issue 8, 2023, 107372, ISSN 2589-0042 – July 12, 2023.
Julien Grogg, Remi Vernet, Emily Charrier, Muriel Urwyler, Olivier Von Rohr, Valentin Saingier, Fabien Courtout, Aurelien Lathuiliere, Nicolas Gaudenzio, Adrien Engel, Nicolas Mach.
Published in iScience, Volume 26, Issue 8, 2023, 107372, ISSN 2589-0042 – July 12, 2023.
Julien Grogg, Remi Vernet, Emily Charrier, Muriel Urwyler, Olivier Von Rohr, Valentin Saingier, Fabien Courtout, Aurelien Lathuiliere, Nicolas Gaudenzio, Adrien Engel, Nicolas Mach.
September 2022 - Transcriptome Analysis of Particulate Matter 2.5-Induced Abnormal Effects on Human Sebocytes
- Transcriptome Analysis of Particulate Matter 2.5-Induced Abnormal Effects on Human Sebocytes
- Published in International Journal of Molecular Science – Int. J. Mol. Sci. 2022, 23(19), 11534; Published: 29 September 2022
(This article belongs to the Special Issue Environmental Toxicant Exposures and Metabolic Disease)- Hye-Won Na, Hyun Soo Kim,Hyunjung, Nari Cha,Young Rok Seo, Yong Deog Hong and Hyoung-June Kim.
- Published in International Journal of Molecular Science – Int. J. Mol. Sci. 2022, 23(19), 11534; Published: 29 September 2022
August 2022 - Immortalized human myoblast cell lines for the delivery of therapeutic proteins using encapsulated cell technology
- Immortalized human myoblast cell lines for the delivery of therapeutic proteins using encapsulated cell technology
- Published in Molecular Therapy Methods & Clinical Development – VOLUME 26, P441-458, SEPTEMBER 08, 2022
- Aurelien Lathuiliere, Remi Vernet, Emily Charrier, Muriel Urwyler, Olivier Von Rohr, Marie-Claude Belkouch, Valentin Saingier, Thomas Bouvarel, Davy Guillarme, Adrien Engel, Patrick Salmon, Thomas Laumonier, Julien Grogg, Nicolas Mach
- Published in Molecular Therapy Methods & Clinical Development – VOLUME 26, P441-458, SEPTEMBER 08, 2022
May 2022 - Mast cell–neuron axis in allergy
- Mast cell–neuron axis in allergy
- Published in Current Opinion in Immunology – Volume 77, August 2022, 102213 – available online as of May 20, 2022
- Nicolas Gaudenzio, Lilian Basso
- Published in Current Opinion in Immunology – Volume 77, August 2022, 102213 – available online as of May 20, 2022
January 2022 - Characterization of a novel non-steroidal glucocorticoid receptor agonist optimized for topical treatment
- Characterization of a novel non-steroidal glucocorticoid receptor agonist optimized for topical treatment
- Published in Nature – Scientific Reports – volume 12, Article number: 1501 (2022)
- Stefan Eirefelt, Martin Stahlhut, Naila Svitacheva, Martin A. Carnerup, Joel Mauricio Correa Da Rosa, David Adrian Ewald, Troels T. Marstrand, Mikkel Krogh-Madsen, Georg Dünstl, Kevin Neil Dack, Anna Ollerstam & Hanne Norsgaard
- Published in Nature – Scientific Reports – volume 12, Article number: 1501 (2022)
January 2022 - Polymethoxyflavones from Kaempferia parviflora ameliorate skin aging in primary human dermal fibroblasts and ex vivo human skin
- Polymethoxyflavones from Kaempferia parviflora ameliorate skin aging in primary human dermal fibroblasts and ex vivo human skin
- Published in Biomedicine & Pharmacotherapy – 2022 Jan;145:112461
- Wannita Klinngam, Phetploy Rungkamoltip, Saowarose Thongin, Jaruwan Joothamongkhon, Phattharachanok Khumkhrong, Mattaka Khongkow, Katawut Namdee, Surapun Tepaamorndech, Puxvadee Chaikul, Mayuree Kanlayavattanakul, Nattaya Lourith, Kitiya Piboonprai, Uracha Ruktanonchai, Udom Asawapirom, Tawin Iempridee
- Published in Biomedicine & Pharmacotherapy – 2022 Jan;145:112461
December 2021 - Barrier disruption, dehydration and inflammation: Investigation of the vicious circle underlying dry skin
- Barrier disruption, dehydration and inflammation: Investigation of the vicious circle underlying dry skin
-
- Published in International Journal of Cosmetic Science – 2021 Dec;43(6):729-737
- Cécile Bize, Erwan Le Gélébart, Alain Moga, Bruno Payré, Christine Garcia
- Published in International Journal of Cosmetic Science – 2021 Dec;43(6):729-737
December 2021 - A hypothetical skin sensitisation next generation risk assessment for coumarin in cosmetic products
- A hypothetical skin sensitisation next generation risk assessment for coumarin in cosmetic products
- Regulatory Toxicology and Pharmacology – 2021, 105075, ISSN 0273-2300
- G. Reynolds, J. Reynolds, N. Gilmour, R. Cubberley, S. Spriggs, A. Aptula, K. Przybylak, S. Windebank, G. Maxwell, M.T. Baltazar
- Regulatory Toxicology and Pharmacology – 2021, 105075, ISSN 0273-2300
November 2021 - A suspended layer additive manufacturing approach to the bioprinting of tri-layered skin equivalents
- A suspended layer additive manufacturing approach to the bioprinting of tri-layered skin equivalents
- Published in APL Bioengineering – 2021 Nov 30;5(4):046103.
- Richard J A Moakes, Jessica J Senior, Thomas E Robinson, Miruna Chipara, Aleksandar Atansov, Amy Naylor, Anthony D Metcalfe, Alan M Smith, Liam M Grover
- Published in APL Bioengineering – 2021 Nov 30;5(4):046103.
October 2021 - The anti-wrinkles properties of sodium acetylated hyaluronate
- The anti-wrinkles properties of sodium acetylated hyaluronate
- Published in Journal of Cosmetic Dermatology – 28 October 2021
- Marie Meunier MS, Amandine Scandolera PhD, Emilie Chapuis BS, Laura Lapierre BS, Jérôme Sandré MD, Gerhard Brunner PhD, Martin Lovchik PhD, Romain Reynaud MS
- Published in Journal of Cosmetic Dermatology – 28 October 2021
October 2021 - A proof-of-concept study utilising 2D NMR spectrometry for in situ characterisation and quantitation of key biomarkers and actives in tape stripped ex vivo human skin
- A proof-of-concept study utilising 2D NMR spectrometry for in situ characterisation and quantitation of key biomarkers and actives in tape-stripped ex vivo human skin
- Published in Talanta – October 2021
- Cameron Robertson, Nidhin Raj b, Robert Lucas b, Tomris Coban a, Adam Le Gresley
- Published in Talanta – October 2021
September 2021 - Clinical brightening efficacy and safety of Melasolv™ (3,4,5-trimethoxy cinnamate thymol ester, TCTE) in Southeast Asian women
- Clinical brightening efficacy and safety of Melasolv™ (3,4,5-trimethoxy cinnamate thymol ester, TCTE) in Southeast Asian women
- Published in Journal of Cosmetic Dermatology – 2021 Sep;20(9):2851-2859
- Seung Hun Kim, Byung Ryol Paik, Sung Hoon Lee, So Mi Lee, Mi Jin Kim, Eun Joo Kim, Chin Yong Leow, Changhui Cho, Won-Seok Park, Byung-Fhy Suh
- Published in Journal of Cosmetic Dermatology – 2021 Sep;20(9):2851-2859
July 2021 - Poster - Mitigation of Injection Site Reactions after Subcutaneous Administration of Dalcinonacog Alfa (DalcA) in Hemophilia B Using Preclinical Models
- Mitigation of Injection Site Reactions after Subcutaneous Administration of Dalcinonacog Alfa (DalcA) in Hemophilia B Using Preclinical Models
- Scientific Poster – ISTH 2021 Congress – Abstract PB0453
- N. Le Moan, L. Kelly, E. Merle, P. Descargues, N. Gaudenzio, H. Gagnon, A. Chatterji, G.E. Blouse
- Scientific Poster – ISTH 2021 Congress – Abstract PB0453
July 2021 - Poster - Assessing subcutaneous injection site reactions by leveraging immunocompetent human skin and artificial intelligence
- Assessing subcutaneous injection site reactions by leveraging immunocompetent human skin and artificial intelligence
- Scientific Poster – CRS 2021 Virtual Annual Meeting – July 25 to 29, 2021.
- Emeline Pagès, Emilie Braun, Eric Merle, Pascal Descargues, Nicolas Gaudenzio
- Scientific Poster – CRS 2021 Virtual Annual Meeting – July 25 to 29, 2021.
March 2021 - Thesis - Development, validation and characterization of a perfused ex vivo human skin model : FlowSkin
- Development, validation and characterization of a perfused ex vivo human skin model : FlowSkin
- PhD Thesis
- Emma Raude, Genoskin
- PhD Thesis
February 2021 - hiPSC-Derived Epidermal Keratinocytes from Ichthyosis Patients Show Altered Expression of Cornification Markers
- hiPSC-Derived Epidermal Keratinocytes from Ichthyosis Patients Show Altered Expression of Cornification Markers
- Published in International Journal of Molecular Sciences – 2021 Feb 11;22(4):1785
- Dulce Lima Cunha, Amanda Oram, Robert Gruber, Roswitha Plank, Arno Lingenhel, Manoj K Gupta, Janine Altmüller, Peter Nürnberg, Matthias Schmuth, Johannes Zschocke, Tomo Šarić, Katja M Eckl, Hans C Hennies
- Published in International Journal of Molecular Sciences – 2021 Feb 11;22(4):1785
February 2021 - Calcipotriol/Betamethasone Dipropionate Foam Inhibits Th17 Cytokine Secretion and Improves Epidermal Barrier Markers in a Human Th17 Skin Inflammation Model
- Calcipotriol/Betamethasone Dipropionate Foam Inhibits Th17 Cytokine Secretion and Improves Epidermal Barrier Markers in a Human Th17 Skin Inflammation Model
- Published in Dermatologic Therapy – 2021 Feb;11(1):265-274
- Paola Lovato, Li Jiang, Josephine Hebsgaard, David A Ewald, Hanne Norsgaard
- Published in Dermatologic Therapy – 2021 Feb;11(1):265-274
January 2021 - Challenges in Developing a Human Model System for Skin Microbiome Research
- Challenges in Developing a Human Model System for Skin Microbiome Research
- Published in Journal of Investigative Dermatology – 2021 Jan;141(1):228-231.e4.
- Peter J Larson, Derrick Chong, Elizabeth Fleming, Julia Oh
- Published in Journal of Investigative Dermatology – 2021 Jan;141(1):228-231.e4.
December 2020 - Active neutrophil responses counteract Candida albicans burn wound infection of ex vivo human skin explants
- Active neutrophil responses counteract Candida albicans burn wound infection of ex vivo human skin explants
- Published in Scientific Reports – 2020 Dec 11;10(1):21818
- Christin von Müller, Fionnuala Bulman, Lysett Wagner, Daniel Rosenberger, Alessandra Marolda, Oliver Kurzai, Petra Eißmann, Ilse D Jacobsen, Birgit Perner, Peter Hemmerich, Slavena Vylkova
- Published in Scientific Reports – 2020 Dec 11;10(1):21818
December 2020 - Standalone or combinatorial phenylbutyrate therapy shows excellent antiviral activity and mimics CREB3 silencing
- Standalone or combinatorial phenylbutyrate therapy shows excellent antiviral activity and mimics CREB3 silencing
- Published in Science Advances – 2020 Dec 4;6(49):eabd9443
- Tejabhiram Yadavalli, Rahul Suryawanshi, Raghuram Koganti, James Hopkins, Joshua Ames, Lulia Koujah, Aqsa Iqbal, Krishnaraju Madavaraju, Alex Agelidis, Deepak Shukla
- Published in Science Advances – 2020 Dec 4;6(49):eabd9443
December 2020 - Photothermally Active Cryogel Devices for Effective Release of Antimicrobial Peptides: On-Demand Treatment of Infections
- Photothermally Active Cryogel Devices for Effective Release of Antimicrobial Peptides: On-Demand Treatment of Infections
- Published in ACS Applied Materials & Interfaces – 2020, 12, 51, 56805–56814
- Laura Chambre, Léa Rosselle, Alexandre Barras, Duygu Aydin, Aleksandra Loczechin, Suzan Gunbay, Rana Sanyal, Nadia Skandrani, Nils Metzler-Nolte, Julia Elisabeth Bandow, Rabah Boukherroub, Sabine Szunerits, and Amitav Sanyal
- Published in ACS Applied Materials & Interfaces – 2020, 12, 51, 56805–56814
November 2020 - Synthesis of Kisspeptin-Mimicking Fragments and Investigation of their Skin Anti-Aging Effects
- Synthesis of Kisspeptin-Mimicking Fragments and Investigation of their Skin Anti-Aging Effects
- Published in International Journal of Molecular Science – 2020 Nov; 21(22): 8439
- Kyung-Eun Lee, Sugyeong Jeong, Seok Kyun Yun, Seoyeon Kyung, Abadie Sophie, Sang Hyun Moh, Hyo Hyun Seo, Myeong Sam Park, Seunghyun Kang, and Hyeonju Yeo
- Published in International Journal of Molecular Science – 2020 Nov; 21(22): 8439
October 2020 - Development and characterization of a human Th17 driven ex vivo skin inflammation model
- Development and characterization of a human Th17‐driven ex vivo skin inflammation model
- Published in Experimental Dermatology – Oct. 2020;29(10):993-1003.
- Claire Jardet, Anthony David, Emilie Braun, Pascal Descargues, Jean-Louis Grolleau, Josephine Hebsgaard, Hanne Norsgaard, Paola Lovato
- Published in Experimental Dermatology – Oct. 2020;29(10):993-1003.
October 2020 - Biomimetic and estrogenic fibers promote tissue repair in mice and human skin via estrogen receptor β
- Biomimetic and estrogenic fibers promote tissue repair in mice and human skin via estrogen receptor β
- Published in Biomaterials – October 2020, PMID: 32521331
- Seungkuk Ahn, Christophe O Chantre, Herdeline Ann M Ardoña, Grant M Gonzalez, Patrick H Campbell, Kevin Kit Parker
- Published in Biomaterials – October 2020, PMID: 32521331
September 2020 - An ‘on-demand’ photothermal antibiotic release cryogel patch: evaluation of efficacy on an ex vivo model for skin wound infection
- An ‘on-demand’ photothermal antibiotic release cryogel patch: evaluation of efficacy on an ex vivo model for skin wound infection
- Published in Biomaterials Science – Sept. 2020 – 21(8), 5911-5919
- Rosselle, L., Cantelmo, A. R., Barras, A., Skandrani, N., Pastore, M., Aydin, D., Chambre, L., Sanyal, R., Sanyal, A., Boukherroub, R., Szunerits, S.
- Published in Biomaterials Science – Sept. 2020 – 21(8), 5911-5919
September 2020 - A novel skin brightening topical technology
- A novel skin brightening topical technology
- Published in Journal of Cosmetic Dermatology – 28 September 2020; 19: 3280– 3285
- Zoe Diana Draelos MD, Isabel Diaz BA, Aaron Cohen PhD, Junhong Mao PhD, Thomas Boyd PhD
- Published in Journal of Cosmetic Dermatology – 28 September 2020; 19: 3280– 3285
August 2020 - The anti-ageing effects of a natural peptide discovered by artificial intelligence
- The antiageing effects of a natural peptide discovered by Artificial Intelligence
- Published in International Journal of Cosmetic Science – August 2020, 42(4)
- Kathy Kennedy, Roi Cal, Rory Casey, Cyril Lopez, Soladis
- Published in International Journal of Cosmetic Science – August 2020, 42(4)
July 2020 - Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging
- Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging
- Published in Clinical Epigenetics volume 12, Article number: 105 (2020)
- Mariana Boroni, Alessandra Zonari, Carolina Reis de Oliveira, Kallie Alkatib, Edgar Andres Ochoa Cruz, Lear E. Brace & Juliana Lott de Carvalho
- Published in Clinical Epigenetics volume 12, Article number: 105 (2020)
April 2020 - Identification of Malassezia furfur Secreted Aspartyl Protease 1 (MfSAP1) and Its Role in Extracellular Matrix Degradation
- Identification of Malassezia furfur Secreted Aspartyl Protease 1 (MfSAP1) and Its Role in Extracellular Matrix Degradation
- Published in Frontiers in Cellular and Infection Microbiology – 2020 Apr 9; 10: 148
- Si En Poh, Joleen P. Z. Goh, Chen Fan, Wisely Chua, Shi Qi Gan, Priscilla Lay Keng Lim, Bhavya Sharma, David I. Leavesley, Thomas L. Dawson, Jr., and Hao Li
- Published in Frontiers in Cellular and Infection Microbiology – 2020 Apr 9; 10: 148
April 2020 - Single-cell transcriptomes of the human skin reveal age-related loss of fibroblast priming
- Single-cell transcriptomes of the human skin reveal age-related loss of fibroblast priming
- Published in Communications Biology volume 3, Article number: 188 (2020)
- Llorenç Solé-Boldo, Günter Raddatz, Sabrina Schütz, Jan-Philipp Mallm, Karsten Rippe, Anke S. Lonsdorf, Manuel Rodríguez-Paredes & Frank Lyko
- Published in Communications Biology volume 3, Article number: 188 (2020)
January 2020 - Mapping 2D- and 3D-distributions of metal/metal oxide nanoparticles within cleared human ex vivo skin tissues
- Mapping 2D- and 3D-distributions of metal/metal oxide nanoparticles within cleared human ex vivo skin tissues
- Published in NanoImpact – 2020 Jan;17:100208
- George J Touloumes, Herdeline Ann M Ardoña, Evan K Casalino, John F Zimmerman, Christophe O Chantre, Dimitrios Bitounis, Philip Demokritou, Kevin Kit Parker
- Published in NanoImpact – 2020 Jan;17:100208
January 2020 - Epidermal and Dermal Hallmarks of Photoaging are Prevented by Treatment with Night Serum Containing Melatonin, Bakuchiol, and Ascorbyl Tetraisopalmitate: In Vitro and Ex Vivo Studies
- Epidermal and Dermal Hallmarks of Photoaging are Prevented by Treatment with Night Serum Containing Melatonin, Bakuchiol, and Ascorbyl Tetraisopalmitate: In Vitro and Ex Vivo Studies
- Published in Dermatology & Therapy (Heidelberg) – 2020 Feb;10(1):191-202.
- Mridvika Narda, Anthony Brown, Béatrice Muscatelli-Groux, Jean A Grimaud, Corinne Granger
- Published in Dermatology & Therapy (Heidelberg) – 2020 Feb;10(1):191-202.
January 2020 - Translational drug discovery and development with the use of tissue-relevant biomarkers: Towards more physiological relevance and better prediction of clinical efficacy
- Translational drug discovery and development with the use of tissue-relevant biomarkers: Towards more physiological relevance and better prediction of clinical efficacy
- Published in Experimental Dermatology – 2020 Jan;29(1):4-14
- Peter Florian, Klaus R Flechsenhar, Eckart Bartnik, Danping Ding-Pfennigdorff, Matthias Herrmann, Paul J Bryce, Frank O Nestle
- Published in Experimental Dermatology – 2020 Jan;29(1):4-14
January 2020 - Anti-Wrinkle Benefits of Peptides Complex Stimulating Skin Basement Membrane Proteins Expression
- Anti-Wrinkle Benefits of Peptides Complex Stimulating Skin Basement Membrane Proteins Expression
- Published in International Journal of Molecular Sciences – 2020 Jan; 21(1): 73
- Sekyoo Jeong, Seokjeong Yoon, Sungwoo Kim, Juyeon Jung, Myungho Kor, Kayoung Shin, Chaejin Lim, Hyo Sun Han, Haekwang Lee, Kyeong-Yong Park, Jinwan Kim, Hwa Jee Chung, and Hyun Jung Kim
- Published in International Journal of Molecular Sciences – 2020 Jan; 21(1): 73
Earlier Scientific Publications
2019 - An Efficient Means to Mitigate Skin Inflammaging by Inhibition of the NLRP3 Inflammasome and Nfkb Pathways: A Novel Epigenetic Mechanism
- An Efficient Means to Mitigate Skin Inflammaging by Inhibition of the NLRP3 Inflammasome and Nfkb Pathways: A Novel Epigenetic Mechanism
- Published in IFSCC Magazine 3 – 2019
- Hanane Chajra, Sandrine Delaunois, David Garandeau, Gaelle Saint-Auret, Marisa Meloni, Eunsun Jung, Mathilde Frechet
- Published in IFSCC Magazine 3 – 2019
November 2019 - Sustained Secretion of the Antimicrobial Peptide S100A7 Is Dependent on the Downregulation of Caspase-8
- Sustained Secretion of the Antimicrobial Peptide S100A7 Is Dependent on the Downregulation of Caspase-8
- Published in Cell Reports – November 26, 2019, Volume 29, Issue 9, P2546-2555.E4
- Tanay Bhatt, Aishwarya Bhosale, Bhavya Bajantri, Mruthyunjaya Swamy Mathapathi, Abrar Rizvi, Giorgio Scita, Amitabha Majumdar, Colin Jamora
- Published in Cell Reports – November 26, 2019, Volume 29, Issue 9, P2546-2555.E4
October 2019 - Improvements of both inflammation and skin barrier in a human Th17 skin inflammation model by topical treatment with fixed-dose combination calcipotriene/betamethasone dipropionate foam
- Improvements of both inflammation and skin barrier in a human Th17 skin inflammation model by topical treatment with fixed-dose combination calcipotriene/betamethasone dipropionate foam
- Published in Journal of the American Academy of Dermatology – October 01, 2019, Volume 81, Issue 4, Supplement 1, AB79
- Hanne Norsgaard, Paola Lovato, Li Jiang, Josephine Hebsgaard, David Adrian Ewald
- Published in Journal of the American Academy of Dermatology – October 01, 2019, Volume 81, Issue 4, Supplement 1, AB79
September 2019 - Peptidylarginine Deiminase Inhibitor Cl-Amidine Attenuates Cornification and Interferes with the Regulation of Autophagy in Reconstructed Human Epidermis
- Peptidylarginine Deiminase Inhibitor Cl-Amidine Attenuates Cornification and Interferes with the Regulation of Autophagy in Reconstructed Human Epidermis
- Published in Journal of Investigative Dermatology – 2019 Sep;139(9):1889-1897.e4.
- Laura Cau, Hidenari Takahara, Paul R Thompson, Guy Serre, Marie-Claire Méchin, Michel Simon
- Published in Journal of Investigative Dermatology – 2019 Sep;139(9):1889-1897.e4.
September 2019 - A human skin model to evaluate the protective effect of compounds against UVA damage
- A human skin model to evaluate the protective effect of compounds against UVA damage
- Published in International Journal of Cosmetic Science – 12 September 2019
- S. Abadie, P. Bedos, J. Rouquette
- Published in International Journal of Cosmetic Science – 12 September 2019
September 2019 - Poster - Scientific Visualisation of Skin Damage caused by Irritants in Human Skin
- Scientific Visualisation of Skin Damage caused by Irritants in Human Skin
- Scientific Poster presented at the 2019 Congress of the European Society for Dermatological Research (ESDR) – September 18-21, 2019
- Nidhin Raj, Robert Lucas, Sarah Coomasaru, Behfar Moghaddam, Ian Francis, Paul McGill – GlaxoSmithKline Consumer Healthcare, Weybridge, United Kingdom
- Scientific Poster presented at the 2019 Congress of the European Society for Dermatological Research (ESDR) – September 18-21, 2019
September 2019 - Poster - Evaluation of pharmacological responses to subcutaneous injection of adalimumab in InflammaSkin®, a full-thickness human ex vivo skin model reproducing key features of psoriatic lesions
- Evaluation of pharmacological responses to subcutaneous injection of adalimumab in InflammaSkin®, a full-thickness human ex vivo skin model reproducing key features of psoriatic lesions
- Scientific Poster presented at the 2019 Congress of the European Society for Dermatological Research (ESDR) – September 18-21, 2019
- C. Jardet (Genoskin), E. Bartnik (Sanofi-Aventis Deutschland), D. Ding-Pfennigdorff (Sanofi-Aventis Deutschland), E. Braun (Genoskin), P. Descargues (Genoskin)
- Scientific Poster presented at the 2019 Congress of the European Society for Dermatological Research (ESDR) – September 18-21, 2019
September 2019 - Poster - Ex vivo visualization and extended release from a dissolvable microarray
- Ex vivo visualization and extended release from a dissolvable microarray
- Scientific Poster presented at the 2019 Congress of the European Society for Dermatological Research (ESDR) – September 18-21, 2019
- K. T. Nielsen, A. H. Eriksson, M. F. Carlsen, K. M. Engel, J. Jansson, K. Petersson, M. A. Røpke, M. Bertelsen, P. Kemp –
LEO Pharma A/S, Ballerup, Denmark
- K. T. Nielsen, A. H. Eriksson, M. F. Carlsen, K. M. Engel, J. Jansson, K. Petersson, M. A. Røpke, M. Bertelsen, P. Kemp –
- Scientific Poster presented at the 2019 Congress of the European Society for Dermatological Research (ESDR) – September 18-21, 2019
September 2019 - Poster - Preservation of human skin integrity and metabolism during 10 days in culture with NativeSkin® system
- Preservation of human skin integrity and metabolism during 10 days in culture with NativeSkin® system
- Scientific Poster presented at the 2019 Congress of the European Society for Dermatological Research (ESDR) – September 18-21, 2019
- E. Raude (Genoskin), E. Pagès (Genoskin), M. Pastore (Genoskin), P.-O. Cuoc (Promega), L. Malaquin (LAAS-CNRS), P. Descargues (Genoskin)
- Scientific Poster presented at the 2019 Congress of the European Society for Dermatological Research (ESDR) – September 18-21, 2019
September 2019 - Poster - Bacterial infection and wound healing in an ex vivo human skin model
- Bacterial infection and wound healing in an ex vivo human skin model
- Scientific Poster presented at the 2019 Congress of the European Society for Dermatological Research (ESDR) – September 18-21, 2019
- E. Pagès (Genoskin), M. Pastore (Genoskin), L. Rosselle (TissueAegis), A. Barras (UMR 8520 – IEMN), N. Skandrani (TissueAegis), A.R. Cantelmo (INSERM U1003), R. Boukherroub (UMR 8520 – IEMN), P. Descargues (Genoskin), S. Szunerits (UMR 8520 – IEMN)
- Scientific Poster presented at the 2019 Congress of the European Society for Dermatological Research (ESDR) – September 18-21, 2019
August 2019 - Near-infrared light activable hydrogels for metformin delivery
- Near-infrared light activable hydrogels for metformin delivery
- Published in Nanoscale – 2019 Aug 29;11(34):15810-15820
- Li Chengnan, Quentin Pagneux, Anna Voronova, Alexandre Barras, Amar Abderrahmani, Valérie Plaisance, Valerie Pawlowski, Nathalie Hennuyer, Bart Staels, Lea Rosselle, Nadia Skandrani, Musen Li, Rabah Boukherroub, Sabine Szunerits
- Published in Nanoscale – 2019 Aug 29;11(34):15810-15820
July 2019 - The Actin-Based Motor Myosin Vb Is Crucial to Maintain Epidermal Barrier Integrity
- The Actin-Based Motor Myosin Vb Is Crucial to Maintain Epidermal Barrier Integrity
- Published in Journal of Investigative Dermatology – July 1, 2019, Volume 139, Issue 7, P1430-1438
- Marie Reynier, Sophie Allart, Dominique Goudounèche, Alain Moga, Guy Serre, Michel Simon, Corinne Leprince
- Published in Journal of Investigative Dermatology – July 1, 2019, Volume 139, Issue 7, P1430-1438
June 2019 - The Amino-Terminal Part of Human FLG2 Is a Component of Cornified Envelopes
- The Amino-Terminal Part of Human FLG2 Is a Component of Cornified Envelopes
- Published in Journal of Investigative Dermatology – 2019 Jun;139(6):1395-1397.
- Géraldine Albérola, Jens-Michael Schröder, Carine Froment, Michel Simon
- Published in Journal of Investigative Dermatology – 2019 Jun;139(6):1395-1397.
December 2018 - Melatonin, bakuchiol and ascorbyl tetraisopalmitate synergize to modulate gene expression and restore Hypoxia-Inducible Factor 1 signaling in UV-exposed skin
- Melatonin, bakuchiol and ascorbyl tetraisopalmitate synergize to modulate gene expression and restore Hypoxia-Inducible Factor 1 signaling in UV-exposed skin
- Published in Cellular and Molecular Biology – 2018 Dec 31;65(8):39-47.
- Mridvika Narda, Anthony Brown, Daniel Pérez-Cremades, José Luís García-Giménez, Corinne Granger
- Published in Cellular and Molecular Biology – 2018 Dec 31;65(8):39-47.
December 2018 - Poster - A fully functional ex vivo human skin model to study human skin microbiome
- A fully functional ex vivo human skin model to study human skin microbiome
- Scientific Poster presented at the BacTouBac meeting of the Paul Sabatier University in Toulouse – December 11 & 12, 2018
- B. Coupe (Vaiomer), M. Pastore (Genoskin), E. Pagès (Genoskin), E. Braun (Genoskin), A. Broha (Vaiomer), P. Descargues (Genoskin)
- Scientific Poster presented at the BacTouBac meeting of the Paul Sabatier University in Toulouse – December 11 & 12, 2018
October 2018 - Phenotypic and lipidomic characterization of primary human epidermal keratinocytes exposed to simulated solar UV radiation
- Phenotypic and lipidomic characterization of primary human epidermal keratinocytes exposed to simulated solar UV radiation
- Published in Journal of Dermatological Science – 2018 Oct;92(1):97-105.
- Núria Dalmau, Nathalie Andrieu-Abadie, Romà Tauler, Carmen Bedia
- Published in Journal of Dermatological Science – 2018 Oct;92(1):97-105.
October 2018 - Myosin phosphatase accelerates cutaneous wound healing by regulating migration and differentiation of epidermal keratinocytes via Akt signaling pathway in human and murine skin
- Myosin phosphatase accelerates cutaneous wound healing by regulating migration and differentiation of epidermal keratinocytes via Akt signaling pathway in human and murine skin
- Published in Molecular Basis of Disease – Biochimica et Biophysica Acta (BBA) – 2018 Oct;1864(10):3268-3280.
- Dániel Horváth, Adrienn Sipos, Evelin Major, Zoltán Kónya, Róbert Bátori, Dóra Dedinszki, Attila Szöll Si, István Tamás, Judit Iván, Andrea Kiss, Ferenc Erd di, Beáta Lontay
- Published in Molecular Basis of Disease – Biochimica et Biophysica Acta (BBA) – 2018 Oct;1864(10):3268-3280.
May 2018 - 3D imaging of cleared human skin biopsies using light-sheet microscopy: A new way to visualize in-depth skin structure
- 3D imaging of cleared human skin biopsies using light-sheet microscopy: A new way to visualize in-depth skin structure
- Published in Skin Research & Technology – 2018 May;24(2):294-303.
- S Abadie, C Jardet, J Colombelli, B Chaput, A David, J-L Grolleau, P Bedos, V Lobjois, P Descargues, J Rouquette
- Published in Skin Research & Technology – 2018 May;24(2):294-303.
May 2018 - Poster - 3D imaging of cleared ex vivo normal human skin, skin appendages and psoriasiform skin lesion using light-sheet microscopy
- 3D imaging of cleared ex vivo normal human skin, skin appendages and psoriasiform skin lesion using light-sheet microscopy
- Scientific Poster presented at the International Investigative Dermatology (IID) 2018 Meeting – 16-19 May 2018
- C. Jardet (Genoskin), S. Abadie (Syntivia), M. Pastore (Genoskin), J. Colombelli (Advanced Digital Microscopy – IRB), B. Chaput (CHU Toulouse Rangueil), A. David (Genoskin), J.-L. Grolleau (CHU Toulouse Rangueil), P. Bedos (Syntivia), V. Lobjois (ITAV), P. Descargues (Genoskin), J. Roquette (ITAV)
- Scientific Poster presented at the International Investigative Dermatology (IID) 2018 Meeting – 16-19 May 2018
May 2018 - Poster - NativeSkin®, an immunocompetent human skin model to study antigen uptake and processing by Langerhans cells
- NativeSkin®, an immunocompetent human skin model to study antigen uptake and processing by Langerhans cells
- Scientific Poster presented at the International Investigative Dermatology (IID) 2018 Meeting – 16-19 May 2018
- E. Pagès (Genoskin), L. Mondoulet (DBV Technologies), E. Bonnefont (Genoskin), E. Braun (Genoskin), V. Dhelft (DBV Technologies), C. Dupont (Hôpital Necker, Université Paris-Descartes), H. Sampson (DBV Technologies), P. Descargues (Genoskin)
- Scientific Poster presented at the International Investigative Dermatology (IID) 2018 Meeting – 16-19 May 2018
March 2018 - Poster - Epicutaneous immunotherapy with peanut directly tragets Langerhans cells in human skin
- Epicutaneous immunotherapy with peanut directly tragets Langerhans cells in human skin
- Scientific Poster presented at the American Academy of Allergy, Asthma & Immunology (AAAAI)/World Allergy Organization (WAO) Joint Congress on March 2-5, 2018.
- Vincent Dioszeghy, Emeline Pages, Christophe Dupont, Hugh A. Sampson, Pascal Descargues, Lucie Mondoulet
- Scientific Poster presented at the American Academy of Allergy, Asthma & Immunology (AAAAI)/World Allergy Organization (WAO) Joint Congress on March 2-5, 2018.
January 2018 - Poster - Evaluation of local inflammatory reactions following subcutaneous injection of a pro-inflammatory cocktail in a fully human ex vivo skin model
- Evaluation of local inflammatory reactions following subcutaneous injection of a pro-inflammatory cocktail in a fully human ex vivo skin model
- Scientific Poster presented at DECHEMA Advances in Medical Biology Seminar – January 30 to 31, 2018
- C. Jardet (Genoskin), E. Pagès (Genoskin), E. Raude (Genoskin), F. Seeliger (AstraZeneca), L. Brandén (AstraZeneca), E. Braun (Genoskin), M. Ingelsten (LAAS-CNRS), P. Descargues (Genoskin)
- Scientific Poster presented at DECHEMA Advances in Medical Biology Seminar – January 30 to 31, 2018
September 2017 - Oxidative damage and impairment of protein quality control systems in keratinocytes exposed to a volatile organic compounds cocktail
- Oxidative damage and impairment of protein quality control systems in keratinocytes exposed to a volatile organic compounds cocktail
- Published in Scientific Reports – 06 September 2017
- Marlène Dezest, Mickael Le Bechec, Laurent Chavatte, Valérie Desauziers, Benoît Chaput, Jean-Louis Grolleau, Pascal Descargues, Carine Nizard, Sylvianne Schnebert, Sylvie Lacombe & Anne-Laure Bulteau
- Published in Scientific Reports – 06 September 2017
September 2017 - Poster - Evaluation of pharmacological responses in a fully human ex vivo skin model following in situ T cell activation with Th17/Th1 psoriasis-like phenotype
- Evaluation of pharmacological responses in a fully human ex vivo skin model following in situ T cell activation with Th17/Th1 psoriasis-like phenotype damage and impairment of protein quality control systems in keratinocytes exposed to a volatile organic compounds cocktail
- Scientific Poster presented at the 47th Annual Meeting of the European Society for Dermatological Research (ESDR) – September 27 to 30, 2017
- P. Lovato (LEO Pharma), C. Jardet (Genoskin), E. Pagès (Genoskin), H. Norsgaard (LEO Pharma), P. Descargues (Genoskin)
- Scientific Poster presented at the 47th Annual Meeting of the European Society for Dermatological Research (ESDR) – September 27 to 30, 2017
June 2017 - SIRT1 activation mediates heat-induced survival of UVB damaged Keratinocytes
- SIRT1 activation mediates heat-induced survival of UVB damaged Keratinocytes
- Published in BMC Dermatology – 10 June 2017
- Leslie Calapre, Elin S. Gray, Sandrine Kurdykowski, Anthony David, Pascal Descargues & Mel Ziman
- Published in BMC Dermatology – 10 June 2017
January 2017 - Mechanistic insights into the impact of Cold Atmospheric Pressure Plasma on human epithelial cell lines
- Mechanistic insights into the impact of Cold Atmospheric Pressure Plasma on human epithelial cell lines
- Published in Scientific Reports – 25 January 2017
- Marlène Dezest, Laurent Chavatte, Marion Bourdens, Damien Quinton, Mylène Camus, Luc Garrigues, Pascal Descargues, Stéphane Arbault, Odile Burlet-Schiltz, Louis Casteilla, Franck Clément, Valérie Planat & Anne-Laure Bulteau
- Published in Scientific Reports – 25 January 2017
2016 - In vitro Dermal Absorption of Hydroquinone: Protocol Validation and Applicability on Illegal Skin-Whitening Cosmetics
- In vitro Dermal Absorption of Hydroquinone: Protocol Validation and Applicability on Illegal Skin-Whitening Cosmetics
- Published in Skin Pharmacology & Physiology – 2016;29(6):300-308.
- Bart Desmedt, Gamze Ates, Patricia Courselle, Jacques O De Beer, Vera Rogiers, Benoit Hendrickx, Eric Deconinck, Kristien De Paepe
- Published in Skin Pharmacology & Physiology – 2016;29(6):300-308.
November 2016 - Integrating targeted gene expression and a skin model system to identify functional inhibitors of the UV activated p38 MAP kinase
- Integrating targeted gene expression and a skin model system to identify functional inhibitors of the UV activated p38 MAP kinase
- Published in Photochemical & Photobiological Sciences – 2016 Nov 30;15(12):1468-1475.
- Amaal Abrahams, Nicolas Mouchet, Nicolas Gouault, Françoise Lohézic Le Dévéhat, Myriam Le Roch, Isabelle Rouaud, David Gilot, Marie-Dominique Galibert
- Published in Photochemical & Photobiological Sciences – 2016 Nov 30;15(12):1468-1475.
October 2016 - Thesis - Development of a human ex vivo melanoma model based on the implantation of tumor spheroids into skin explants
- Development of a human ex vivo melanoma model based on the implantation of tumor spheroids into skin explants
- PhD Thesis
- Claire Jardet, Genoskin COO
- PhD Thesis
May 2016 - Heat-mediated reduction of apoptosis in UVB-damaged keratinocytes in vitro and in human skin ex vivo
- Heat-mediated reduction of apoptosis in UVB-damaged keratinocytes in vitro and in human skin ex vivo
- Published in BMC Dermatology – 2016 May 26;16(1):6.
- Leslie Calapre, Elin S Gray, Sandrine Kurdykowski, Anthony David, Prue Hart, Pascal Descargues, Mel Ziman
- Published in BMC Dermatology – 2016 May 26;16(1):6.
October 2015 - In vitro and in vivo dermal absorption assessment of acetyl aspartic acid: a compartmental study
- In vitro and in vivo dermal absorption assessment of acetyl aspartic acid: a compartmental study
- Published in International Journal of Cosmetic Science – 2015 Oct;37 Suppl 1:34-40.
- L Duracher, L Visdal-Johnsen, A Mavon
- Published in International Journal of Cosmetic Science – 2015 Oct;37 Suppl 1:34-40.
October 2015 - Safety assessment of a novel active ingredient, acetyl aspartic acid, according to the EU Cosmetics Regulation and the Scientific Committee on Consumer Safety guidelines
- Safety assessment of a novel active ingredient, acetyl aspartic acid, according to the EU Cosmetics Regulation and the Scientific Committee on Consumer Safety guidelines
- Published in International Journal of Cosmetic Science – 2015 Oct;37 Suppl 1:21-7.
- P Daly, G Moran
- Published in International Journal of Cosmetic Science – 2015 Oct;37 Suppl 1:21-7.
March 2015 - A Novel Explant Model for Skin Delivery Assessment
- A Novel Explant Model for Skin Delivery Assessment
- Published in Cosmetics & Toiletries – March 1, 2015
- Lucie Duracher, PhD; Lene Visdal-Johnsen, PhD; and Alain Mavon, PhD; Sandrine Kurdykowski, PhD; and Pascal Descargues, PhD
- Published in Cosmetics & Toiletries – March 1, 2015
March 2015 - Human Skin Models for Research Applications in Pharmacology and Toxicology: Introducing NativeSkin®, the “Missing Link” Bridging Cell Culture and/or Reconstructed Skin Models and Human Clinical Testing
- Human Skin Models for Research Applications in Pharmacology and Toxicology: Introducing NativeSkin®, the “Missing Link” Bridging Cell Culture and/or Reconstructed Skin Models and Human Clinical Testing
- Published in Applied In Vitro Toxicology – 6 March 2015 Vol. 1, No.1
- Bart De Wever, Sandrine Kurdykowski, and Pascal Descargues
- Published in Applied In Vitro Toxicology – 6 March 2015 Vol. 1, No.1
October 2014 - Calcipotriol counteracts betamethasone-induced decrease in extracellular matrix components related to skin atrophy
- Calcipotriol counteracts betamethasone-induced decrease in extracellular matrix components related to skin atrophy
- Published in Archives of Dermatological Research – 2014 Oct;306(8):719-29.
- Hanne Norsgaard, Sandrine Kurdykowski, Pascal Descargues, Tatiana Gonzalez, Troels Marstrand, Georg Dünstl, Mads Røpke
- Published in Archives of Dermatological Research – 2014 Oct;306(8):719-29.
