Vaccine Development

Top-level science through the eyes of an expert.Preclinical evaluation of an energy-driven device for localized skin delivery of nucleic acidsDid you miss the live session? The full webinar recording is now available to watch on demand. Explore preclinical insights into an energy-driven, microneedle-based device enabling localized, non-viral delivery of naked nucleic acids to skin, highlighting transgene expression, immune activation, andRead more

Explore how HypoSkin®—a standardized, injectable, and immunocompetent human skin model—provides a translational, animal-free solution for assessing the immunogenicity of therapeutic compounds. From structural stability to real-time immune response profiling, this white paper delivers data-backed insights designed for pharma and biotech teams advancing injectable drug development.

Vaccine DevelopmentVaxSkin® an innovative platform to study vaccine immunogenicityUnlocking vaccine immunogenicity insights with VaxSkin® Understanding early immune responses to vaccination is essential for developing safe and effective vaccines. However, conventional preclinical models often struggle to reproduce the complexity of human skin immunity, particularly the interactions between resident immune cells at the injection site. In this application note, we explore howRead more

The future of vaccine researchThe rapid advancements in vaccine research over the past decade have transformed the way we prevent and respond to infectious diseases. The COVID-19 pandemic accelerated the development of novel platforms like mRNA vaccines, showcasing the potential for rapid innovation. However, despite these breakthroughs, significant challenges remain in vaccine research, including preclinical model limitations, immune variability, theRead more

From human skin to human data: Advancing immunogenicity testing with human modelsIn a public workshop organized by the FDA-CRCG group, Dr. Nicolas Gaudenzio, CSO of Genoskin, introduced an innovative platform for assessing immune reactions in response to injected substances using human skin explants. His talk, titled "A new in vitro framework for assessing immunogenicity using comprehensive profiling of injectable humanRead more

The landscape of vaccine research is undergoing an important transformation, thanks to the breakthroughs in mRNA vaccine technology.